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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRHL3
All Species:
4.24
Human Site:
T614
Identified Species:
11.67
UniProt:
Q8TE85
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE85
NP_067003.2
626
70345
T614
L
D
S
N
P
S
P
T
T
V
N
S
L
H
F
Chimpanzee
Pan troglodytes
XP_513205
603
67881
L587
S
N
H
V
A
F
L
L
D
M
G
E
L
D
G
Rhesus Macaque
Macaca mulatta
XP_001105318
622
69645
T610
L
D
S
N
P
S
P
T
T
V
N
S
L
H
L
Dog
Lupus familis
XP_544497
636
71295
L620
S
N
H
V
A
F
L
L
D
M
G
E
L
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWH3
603
67798
L587
S
N
H
V
A
F
L
L
D
M
G
E
L
D
G
Rat
Rattus norvegicus
NP_001100160
549
61703
L538
F
L
L
D
M
G
E
L
D
G
K
I
Q
I
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506957
618
70066
A607
F
Q
L
Q
I
E
E
A
G
G
S
Y
K
L
T
Chicken
Gallus gallus
Frog
Xenopus laevis
Q5PPL8
595
68393
D583
A
F
L
L
D
L
T
D
V
D
G
K
I
Q
V
Zebra Danio
Brachydanio rerio
XP_001923763
613
69690
I596
S
N
E
D
T
F
Q
I
Q
M
E
E
M
G
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.7
94.7
84.2
N.A.
82.9
75.2
N.A.
44
N.A.
60.8
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.9
95.3
88.3
N.A.
89.1
80.9
N.A.
61
N.A.
73
61.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
6.6
N.A.
6.6
0
N.A.
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
93.3
20
N.A.
20
6.6
N.A.
6.6
N.A.
6.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
0
0
34
0
0
12
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
23
0
23
12
0
0
12
45
12
0
0
0
34
0
% D
% Glu:
0
0
12
0
0
12
23
0
0
0
12
45
0
0
0
% E
% Phe:
23
12
0
0
0
45
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
0
0
0
0
12
0
0
12
23
45
0
0
12
45
% G
% His:
0
0
34
0
0
0
0
0
0
0
0
0
0
23
0
% H
% Ile:
0
0
0
0
12
0
0
12
0
0
0
12
12
12
12
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
12
12
12
0
0
% K
% Leu:
23
12
34
12
0
12
34
45
0
0
0
0
56
12
12
% L
% Met:
0
0
0
0
12
0
0
0
0
45
0
0
12
0
0
% M
% Asn:
0
45
0
23
0
0
0
0
0
0
23
0
0
0
0
% N
% Pro:
0
0
0
0
23
0
23
0
0
0
0
0
0
0
0
% P
% Gln:
0
12
0
12
0
0
12
0
12
0
0
0
12
12
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
45
0
23
0
0
23
0
0
0
0
12
23
0
0
0
% S
% Thr:
0
0
0
0
12
0
12
23
23
0
0
0
0
0
12
% T
% Val:
0
0
0
34
0
0
0
0
12
23
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _