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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L1
All Species:
16.97
Human Site:
Y416
Identified Species:
46.67
UniProt:
Q8TE68
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE68
NP_060199.3
723
80309
Y416
S
P
E
E
G
P
P
Y
R
P
E
F
F
S
G
Chimpanzee
Pan troglodytes
XP_512904
745
82543
Y451
P
P
E
E
G
P
P
Y
R
P
E
F
F
S
G
Rhesus Macaque
Macaca mulatta
XP_001086805
748
82645
Y446
P
P
E
E
G
P
P
Y
R
P
E
F
F
S
G
Dog
Lupus familis
XP_541418
686
75582
Y395
S
P
K
E
G
P
P
Y
S
P
E
F
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5F8
716
80009
Y416
P
P
E
E
G
S
P
Y
S
P
E
F
Y
N
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517371
311
34464
H41
P
V
E
K
Q
H
Q
H
E
R
R
R
S
Q
V
Chicken
Gallus gallus
XP_001232098
722
82297
T417
P
R
E
A
N
I
P
T
Y
I
P
K
F
R
N
Frog
Xenopus laevis
NP_001084577
787
87485
P421
P
K
E
Q
F
I
P
P
Y
I
P
R
F
R
N
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
L402
P
K
D
Q
C
A
P
L
Y
V
P
K
F
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.6
78
N.A.
85.3
N.A.
N.A.
30.1
39.8
38.5
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.9
93.7
82.8
N.A.
90
N.A.
N.A.
34.2
60.1
56.2
58.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
80
N.A.
66.6
N.A.
N.A.
6.6
20
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
80
N.A.
N.A.
20
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
78
56
0
0
0
0
12
0
56
0
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
56
67
0
0
% F
% Gly:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
56
% G
% His:
0
0
0
0
0
12
0
12
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
23
0
0
0
23
0
0
0
0
0
% I
% Lys:
0
23
12
12
0
0
0
0
0
0
0
23
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
0
0
0
0
0
0
0
12
34
% N
% Pro:
78
56
0
0
0
45
89
12
0
56
34
0
0
0
0
% P
% Gln:
0
0
0
23
12
0
12
0
0
0
0
0
0
12
0
% Q
% Arg:
0
12
0
0
0
0
0
0
34
12
12
23
0
34
0
% R
% Ser:
23
0
0
0
0
12
0
0
23
0
0
0
23
45
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% T
% Val:
0
12
0
0
0
0
0
0
0
12
0
0
0
0
12
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
56
34
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _