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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L1
All Species:
10.3
Human Site:
S476
Identified Species:
28.33
UniProt:
Q8TE68
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TE68
NP_060199.3
723
80309
S476
E
S
E
P
Q
L
E
S
E
T
A
G
K
W
V
Chimpanzee
Pan troglodytes
XP_512904
745
82543
S511
E
S
E
P
Q
L
E
S
E
T
A
G
K
W
V
Rhesus Macaque
Macaca mulatta
XP_001086805
748
82645
S506
E
S
E
P
Q
L
E
S
E
T
A
G
K
W
V
Dog
Lupus familis
XP_541418
686
75582
Q451
Q
P
E
A
E
P
Q
Q
E
P
E
G
K
W
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8R5F8
716
80009
E475
L
E
T
E
S
Q
L
E
E
K
A
R
K
W
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517371
311
34464
D94
E
L
S
V
S
H
R
D
V
L
E
V
L
D
D
Chicken
Gallus gallus
XP_001232098
722
82297
M494
R
N
F
E
A
Q
A
M
A
Q
P
K
R
Y
A
Frog
Xenopus laevis
NP_001084577
787
87485
Q490
G
N
F
E
E
C
G
Q
S
E
P
Q
K
Y
A
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
S460
S
N
G
S
Y
P
P
S
P
A
P
R
K
Y
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.4
92.6
78
N.A.
85.3
N.A.
N.A.
30.1
39.8
38.5
37.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
93.9
93.7
82.8
N.A.
90
N.A.
N.A.
34.2
60.1
56.2
58.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
40
N.A.
33.3
N.A.
N.A.
6.6
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
60
N.A.
33.3
N.A.
N.A.
6.6
20
26.6
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
12
0
12
0
12
12
45
0
0
0
34
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
12
0
0
0
0
0
12
12
% D
% Glu:
45
12
45
34
23
0
34
12
56
12
23
0
0
0
0
% E
% Phe:
0
0
23
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
12
0
0
0
12
0
0
0
0
45
0
0
0
% G
% His:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
12
78
0
0
% K
% Leu:
12
12
0
0
0
34
12
0
0
12
0
0
12
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
0
34
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
12
0
34
0
23
12
0
12
12
34
0
0
0
0
% P
% Gln:
12
0
0
0
34
23
12
23
0
12
0
12
0
0
0
% Q
% Arg:
12
0
0
0
0
0
12
0
0
0
0
23
12
0
0
% R
% Ser:
12
34
12
12
23
0
0
45
12
0
0
0
0
0
0
% S
% Thr:
0
0
12
0
0
0
0
0
0
34
0
0
0
0
0
% T
% Val:
0
0
0
12
0
0
0
0
12
0
0
12
0
0
56
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
56
0
% W
% Tyr:
0
0
0
0
12
0
0
0
0
0
0
0
0
34
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _