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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ACTRT2 All Species: 19.7
Human Site: S251 Identified Species: 39.39
UniProt: Q8TDY3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDY3 NP_536356.3 377 41702 S251 L P D G N I I S L G D P L H Q
Chimpanzee Pan troglodytes XP_524851 377 41655 S251 L P D G N I I S L G D P L H Q
Rhesus Macaque Macaca mulatta XP_001112288 377 41464 S251 L P D G N I I S L G D P L Y Q
Dog Lupus familis XP_536719 377 41664 C251 L P D G N I I C V G E Q L Y Q
Cat Felis silvestris
Mouse Mus musculus Q9D9L5 377 41597 Y251 L P D G N V I Y I G D Q L Y Q
Rat Rattus norvegicus Q5XIK1 376 42176 Q250 L P D G N T I Q M S D H L C Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506410 376 41777 R250 L P N G Q A I R I G K Q L F L
Chicken Gallus gallus P08023 377 41976 T251 L P D G Q V I T I G N E R F R
Frog Xenopus laevis O93400 375 41748 V247 Y E L P D G Q V I T I G N E R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres P68142 375 41748 T249 L P D G Q V I T I G N E R F R
Fruit Fly Dros. melanogaster P02574 376 41768 V248 Y E L P D G Q V I T I G N E R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P10984 376 41759 V248 Y E L P D G Q V I T V G N E R
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 95.4 85.1 N.A. 80.6 66 N.A. 64.4 48.5 48.5 N.A. 48.2 48.2 N.A. 48.5 N.A.
Protein Similarity: 100 99.1 97.3 91.7 N.A. 89.1 77.9 N.A. 80.6 66.8 67.3 N.A. 67.1 67.6 N.A. 67.6 N.A.
P-Site Identity: 100 100 93.3 66.6 N.A. 66.6 60 N.A. 40 40 0 N.A. 40 0 N.A. 0 N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 86.6 66.6 N.A. 53.3 73.3 20 N.A. 73.3 20 N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 9 0 0 0 0 0 9 0 % C
% Asp: 0 0 67 0 25 0 0 0 0 0 42 0 0 0 0 % D
% Glu: 0 25 0 0 0 0 0 0 0 0 9 17 0 25 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % F
% Gly: 0 0 0 75 0 25 0 0 0 67 0 25 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % H
% Ile: 0 0 0 0 0 34 75 0 59 0 17 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 75 0 25 0 0 0 0 0 25 0 0 0 59 0 9 % L
% Met: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 0 9 0 50 0 0 0 0 0 17 0 25 0 0 % N
% Pro: 0 75 0 25 0 0 0 0 0 0 0 25 0 0 0 % P
% Gln: 0 0 0 0 25 0 25 9 0 0 0 25 0 0 50 % Q
% Arg: 0 0 0 0 0 0 0 9 0 0 0 0 17 0 42 % R
% Ser: 0 0 0 0 0 0 0 25 0 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 17 0 25 0 0 0 0 0 % T
% Val: 0 0 0 0 0 25 0 25 9 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 25 0 0 0 0 0 0 9 0 0 0 0 0 25 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _