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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK7
All Species:
45.76
Human Site:
Y255
Identified Species:
83.89
UniProt:
Q8TDX7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDX7
NP_598001.1
302
34551
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Chimpanzee
Pan troglodytes
XP_001138236
432
48499
Y385
Q
K
I
E
Q
C
D
Y
P
P
L
P
G
E
H
Rhesus Macaque
Macaca mulatta
XP_001110532
302
34516
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Dog
Lupus familis
XP_537129
302
34516
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES74
302
34518
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Rat
Rattus norvegicus
P59895
313
35817
Y266
Q
K
I
E
Q
C
D
Y
P
P
L
P
G
E
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509791
504
55648
D456
C
Q
H
L
E
Q
C
D
I
P
A
L
P
R
A
Chicken
Gallus gallus
NP_001026435
302
34555
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Frog
Xenopus laevis
NP_001084755
302
34589
Y255
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Zebra Danio
Brachydanio rerio
NP_001003617
297
34215
Y251
K
K
I
E
Q
C
D
Y
P
P
L
P
S
D
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_510080
302
34559
Y244
K
K
I
E
N
C
E
Y
P
P
L
P
A
D
I
Sea Urchin
Strong. purpuratus
XP_781870
294
33867
Y246
K
K
I
D
K
C
D
Y
P
P
L
P
A
D
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22209
435
51185
T307
I
K
N
G
K
C
D
T
V
P
E
Y
Y
S
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.4
99.3
99.3
N.A.
97.6
77
N.A.
47.8
98
95
87
N.A.
N.A.
N.A.
68.8
78.1
Protein Similarity:
100
64.5
99.6
99.6
N.A.
99.3
85.9
N.A.
53.9
98.3
96.6
93.3
N.A.
N.A.
N.A.
80.7
85.1
P-Site Identity:
100
80
100
100
N.A.
100
80
N.A.
6.6
100
100
100
N.A.
N.A.
N.A.
73.3
80
P-Site Similarity:
100
93.3
100
100
N.A.
100
93.3
N.A.
20
100
100
100
N.A.
N.A.
N.A.
86.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
16
0
8
% A
% Cys:
8
0
0
0
0
93
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
85
8
0
0
0
0
0
70
0
% D
% Glu:
0
0
0
77
8
0
8
0
0
0
8
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
16
0
0
% G
% His:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
77
% H
% Ile:
8
0
85
0
0
0
0
0
8
0
0
0
0
0
8
% I
% Lys:
70
93
0
0
16
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
0
0
85
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
85
100
0
85
8
0
0
% P
% Gln:
16
8
0
0
70
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
54
8
0
% S
% Thr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
85
0
0
0
8
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _