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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT3
All Species:
33.64
Human Site:
Y4427
Identified Species:
61.67
UniProt:
Q8TDW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDW7
NP_001008781.2
4589
505523
Y4427
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Chimpanzee
Pan troglodytes
XP_001136982
4601
507102
Y4439
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Rhesus Macaque
Macaca mulatta
XP_001084587
4609
507875
Y4447
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Dog
Lupus familis
XP_848507
4589
505147
Y4427
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
Y4393
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Rat
Rattus norvegicus
Q8R508
4555
502069
Y4393
R
E
L
E
S
D
Y
Y
L
G
G
Y
D
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
Y4113
H
P
A
E
L
Q
E
Y
P
R
Y
E
L
I
Q
Chicken
Gallus gallus
NP_001104793
4557
501888
Y4396
R
E
L
E
T
D
Y
Y
L
G
G
Y
D
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998132
4610
506620
Y4432
A
L
L
D
T
D
Y
Y
P
G
G
Y
D
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
S4538
A
D
S
S
S
L
H
S
N
D
S
N
E
S
K
Honey Bee
Apis mellifera
XP_394631
3607
400577
V3447
E
D
Q
E
S
E
Y
V
G
D
S
E
C
G
T
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
S4132
S
D
I
R
D
S
R
S
P
S
A
C
G
S
S
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
D3690
S
H
I
N
E
E
E
D
D
Y
E
T
D
E
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.9
95.5
N.A.
91.9
92.3
N.A.
40
86.4
N.A.
50.6
N.A.
36
31.2
26.7
21.7
Protein Similarity:
100
98.8
98.3
98.3
N.A.
96.2
96.4
N.A.
57.6
93.3
N.A.
69.1
N.A.
54.8
46.1
46.9
39.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
20
93.3
N.A.
60
N.A.
6.6
20
0
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
N.A.
80
N.A.
26.6
33.3
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
8
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
8
8
0
0
% C
% Asp:
0
24
0
8
8
62
0
8
8
16
0
0
70
0
62
% D
% Glu:
8
54
0
70
8
16
16
0
0
0
8
16
8
8
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
62
62
0
8
8
0
% G
% His:
8
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
0
0
0
0
0
70
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
8
62
0
8
8
0
0
54
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
8
0
0
0
0
0
0
24
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
8
% Q
% Arg:
54
0
0
8
0
0
8
0
0
8
0
0
0
0
0
% R
% Ser:
16
0
8
8
62
8
0
16
0
8
16
0
0
16
8
% S
% Thr:
0
0
0
0
16
0
0
0
0
0
0
8
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
70
70
0
8
8
62
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _