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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT3 All Species: 6.36
Human Site: T4265 Identified Species: 11.67
UniProt: Q8TDW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDW7 NP_001008781.2 4589 505523 T4265 G E H Q E M T T F H P E S P R
Chimpanzee Pan troglodytes XP_001136982 4601 507102 R4277 G P P Q V P V R P M A Y T P C
Rhesus Macaque Macaca mulatta XP_001084587 4609 507875 R4285 G P P Q V P V R P M A Y T P C
Dog Lupus familis XP_848507 4589 505147 T4265 G E P Q E M T T F H P E S P R
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 R4231 G P P Q V P V R P M A Y T P C
Rat Rattus norvegicus Q8R508 4555 502069 R4231 G P P Q V P V R P M A Y T P C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 P3951 L E L S D G A P H L Q Y H C P
Chicken Gallus gallus NP_001104793 4557 501888 R4234 G P P Q V P V R P M A Y T P C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998132 4610 506620 S4270 S Y T P S I P S D S R N N L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 Y4376 V N Q R P I S Y T A V P N D N
Honey Bee Apis mellifera XP_394631 3607 400577 P3285 R S T P V P P P S L T L A N P
Nematode Worm Caenorhab. elegans Q19319 4292 477180 R3970 T G K H C E A R G F E D H E T
Sea Urchin Strong. purpuratus XP_785422 3852 424350 L3528 P T D S E S D L P F M D R D P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 95.5 N.A. 91.9 92.3 N.A. 40 86.4 N.A. 50.6 N.A. 36 31.2 26.7 21.7
Protein Similarity: 100 98.8 98.3 98.3 N.A. 96.2 96.4 N.A. 57.6 93.3 N.A. 69.1 N.A. 54.8 46.1 46.9 39.2
P-Site Identity: 100 20 20 93.3 N.A. 20 20 N.A. 6.6 20 N.A. 0 N.A. 0 0 0 6.6
P-Site Similarity: 100 26.6 26.6 93.3 N.A. 26.6 26.6 N.A. 13.3 26.6 N.A. 20 N.A. 26.6 6.6 6.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 16 0 0 8 39 0 8 0 0 % A
% Cys: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 39 % C
% Asp: 0 0 8 0 8 0 8 0 8 0 0 16 0 16 8 % D
% Glu: 0 24 0 0 24 8 0 0 0 0 8 16 0 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 16 16 0 0 0 0 0 % F
% Gly: 54 8 0 0 0 8 0 0 8 0 0 0 0 0 0 % G
% His: 0 0 8 8 0 0 0 0 8 16 0 0 16 0 0 % H
% Ile: 0 0 0 0 0 16 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 8 0 8 0 0 0 0 8 0 16 0 8 0 8 0 % L
% Met: 0 0 0 0 0 16 0 0 0 39 8 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 8 16 8 8 % N
% Pro: 8 39 47 16 8 47 16 16 47 0 16 8 0 54 24 % P
% Gln: 0 0 8 54 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 8 0 0 8 0 0 0 47 0 0 8 0 8 0 16 % R
% Ser: 8 8 0 16 8 8 8 8 8 8 0 0 16 0 0 % S
% Thr: 8 8 16 0 0 0 16 16 8 0 8 0 39 0 8 % T
% Val: 8 0 0 0 47 0 39 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 8 0 0 0 47 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _