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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT3 All Species: 27.58
Human Site: S4473 Identified Species: 50.56
UniProt: Q8TDW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDW7 NP_001008781.2 4589 505523 S4473 L P P S Q P V S L A S T L S P
Chimpanzee Pan troglodytes XP_001136982 4601 507102 S4485 L P P S Q P V S L A S T L S P
Rhesus Macaque Macaca mulatta XP_001084587 4609 507875 S4493 L P P S Q P V S L A S T L S P
Dog Lupus familis XP_848507 4589 505147 S4473 L P P S Q P V S L A G T L S P
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 S4439 L P P S Q P T S L T S T M S P
Rat Rattus norvegicus Q8R508 4555 502069 S4439 L P P S Q P T S L T G T M S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 P4158 D Q S N K R A P I P P R Y S N
Chicken Gallus gallus NP_001104793 4557 501888 S4442 L P P S Q P V S M A N T L S P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998132 4610 506620 H4492 P G G S S I R H R P P L P Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 M4589 E S C L E P F M L P R S S N Q
Honey Bee Apis mellifera XP_394631 3607 400577 N3492 E S Y L R H P N S Y L P H Y N
Nematode Worm Caenorhab. elegans Q19319 4292 477180 S4177 P R G D V L S S L R D S S D E
Sea Urchin Strong. purpuratus XP_785422 3852 424350 Y3737 Y P P M D D D Y G G L P L N A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 95.5 N.A. 91.9 92.3 N.A. 40 86.4 N.A. 50.6 N.A. 36 31.2 26.7 21.7
Protein Similarity: 100 98.8 98.3 98.3 N.A. 96.2 96.4 N.A. 57.6 93.3 N.A. 69.1 N.A. 54.8 46.1 46.9 39.2
P-Site Identity: 100 100 100 93.3 N.A. 80 73.3 N.A. 6.6 86.6 N.A. 6.6 N.A. 13.3 0 13.3 20
P-Site Similarity: 100 100 100 93.3 N.A. 86.6 80 N.A. 26.6 100 N.A. 6.6 N.A. 33.3 13.3 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 8 0 0 39 0 0 0 0 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 0 8 8 8 8 0 0 0 8 0 0 8 0 % D
% Glu: 16 0 0 0 8 0 0 0 0 0 0 0 0 0 8 % E
% Phe: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % F
% Gly: 0 8 16 0 0 0 0 0 8 8 16 0 0 0 0 % G
% His: 0 0 0 0 0 8 0 8 0 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 54 0 0 16 0 8 0 0 62 0 16 8 47 0 8 % L
% Met: 0 0 0 8 0 0 0 8 8 0 0 0 16 0 0 % M
% Asn: 0 0 0 8 0 0 0 8 0 0 8 0 0 16 16 % N
% Pro: 16 62 62 0 0 62 8 8 0 24 16 16 8 0 54 % P
% Gln: 0 8 0 0 54 0 0 0 0 0 0 0 0 8 8 % Q
% Arg: 0 8 0 0 8 8 8 0 8 8 8 8 0 0 0 % R
% Ser: 0 16 8 62 8 0 8 62 8 0 31 16 16 62 0 % S
% Thr: 0 0 0 0 0 0 16 0 0 16 0 54 0 0 0 % T
% Val: 0 0 0 0 8 0 39 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 8 0 0 0 0 8 0 8 0 0 8 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _