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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT3
All Species:
25.76
Human Site:
S4469
Identified Species:
47.22
UniProt:
Q8TDW7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDW7
NP_001008781.2
4589
505523
S4469
Q
Y
E
A
L
P
P
S
Q
P
V
S
L
A
S
Chimpanzee
Pan troglodytes
XP_001136982
4601
507102
S4481
Q
Y
E
A
L
P
P
S
Q
P
V
S
L
A
S
Rhesus Macaque
Macaca mulatta
XP_001084587
4609
507875
S4489
Q
Y
E
A
L
P
P
S
Q
P
V
S
L
A
S
Dog
Lupus familis
XP_848507
4589
505147
S4469
Q
Y
E
A
L
P
P
S
Q
P
V
S
L
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
S4435
Q
Y
E
A
L
P
P
S
Q
P
T
S
L
T
S
Rat
Rattus norvegicus
Q8R508
4555
502069
S4435
Q
Y
E
A
L
P
P
S
Q
P
T
S
L
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
N4154
P
F
P
L
D
Q
S
N
K
R
A
P
I
P
P
Chicken
Gallus gallus
NP_001104793
4557
501888
S4438
Q
Y
E
T
L
P
P
S
Q
P
V
S
M
A
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998132
4610
506620
S4488
T
P
S
S
P
G
G
S
S
I
R
H
R
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
L4585
D
S
E
A
E
S
C
L
E
P
F
M
L
P
R
Honey Bee
Apis mellifera
XP_394631
3607
400577
L3488
Y
K
G
S
E
S
Y
L
R
H
P
N
S
Y
L
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
D4173
D
R
K
D
P
R
G
D
V
L
S
S
L
R
D
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
M3733
E
L
E
N
Y
P
P
M
D
D
D
Y
G
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.9
95.5
N.A.
91.9
92.3
N.A.
40
86.4
N.A.
50.6
N.A.
36
31.2
26.7
21.7
Protein Similarity:
100
98.8
98.3
98.3
N.A.
96.2
96.4
N.A.
57.6
93.3
N.A.
69.1
N.A.
54.8
46.1
46.9
39.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
80
N.A.
0
80
N.A.
6.6
N.A.
26.6
0
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
80
N.A.
26.6
93.3
N.A.
13.3
N.A.
33.3
20
20
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
54
0
0
0
0
0
0
8
0
0
39
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
16
0
0
8
8
0
0
8
8
8
8
0
0
0
8
% D
% Glu:
8
0
70
0
16
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
8
16
0
0
0
0
0
8
8
16
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
8
8
0
0
0
0
0
8
0
0
0
0
0
0
% K
% Leu:
0
8
0
8
54
0
0
16
0
8
0
0
62
0
16
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
8
8
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
8
% N
% Pro:
8
8
8
0
16
62
62
0
0
62
8
8
0
24
16
% P
% Gln:
54
0
0
0
0
8
0
0
54
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
8
0
0
8
8
8
0
8
8
8
% R
% Ser:
0
8
8
16
0
16
8
62
8
0
8
62
8
0
31
% S
% Thr:
8
0
0
8
0
0
0
0
0
0
16
0
0
16
0
% T
% Val:
0
0
0
0
0
0
0
0
8
0
39
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
54
0
0
8
0
8
0
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _