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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT3 All Species: 27.88
Human Site: S4398 Identified Species: 51.11
UniProt: Q8TDW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDW7 NP_001008781.2 4589 505523 S4398 W M P G A R L S D I E E V P N
Chimpanzee Pan troglodytes XP_001136982 4601 507102 S4410 W M P G A R L S D I E E V P N
Rhesus Macaque Macaca mulatta XP_001084587 4609 507875 S4418 W M P G A R L S D I E E V P N
Dog Lupus familis XP_848507 4589 505147 S4398 W M P G A R L S D I E E V P N
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 S4364 W M P G A R L S D I E E M P N
Rat Rattus norvegicus Q8R508 4555 502069 S4364 W M P G A R L S D I E E M P N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 G4084 Q N P C L N D G L C L E T P I
Chicken Gallus gallus NP_001104793 4557 501888 S4367 W M P S A R L S D I E E V P N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998132 4610 506620 P4403 W M P S V Q L P G I Q E F P Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 S4509 G Q Y H W D C S D W V R K S H
Honey Bee Apis mellifera XP_394631 3607 400577 N3418 S N E S N E S N T H Q L P S V
Nematode Worm Caenorhab. elegans Q19319 4292 477180 N4103 G F R N D S S N F I S T S S V
Sea Urchin Strong. purpuratus XP_785422 3852 424350 N3661 V Q H P E S L N N I P E I P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 95.5 N.A. 91.9 92.3 N.A. 40 86.4 N.A. 50.6 N.A. 36 31.2 26.7 21.7
Protein Similarity: 100 98.8 98.3 98.3 N.A. 96.2 96.4 N.A. 57.6 93.3 N.A. 69.1 N.A. 54.8 46.1 46.9 39.2
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 20 93.3 N.A. 46.6 N.A. 13.3 0 6.6 26.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 93.3 N.A. 60 N.A. 20 13.3 13.3 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 54 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 8 0 0 8 0 0 8 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 8 8 0 62 0 0 0 0 0 0 % D
% Glu: 0 0 8 0 8 8 0 0 0 0 54 77 0 0 0 % E
% Phe: 0 8 0 0 0 0 0 0 8 0 0 0 8 0 0 % F
% Gly: 16 0 0 47 0 0 0 8 8 0 0 0 0 0 0 % G
% His: 0 0 8 8 0 0 0 0 0 8 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 77 0 0 8 0 8 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 8 0 70 0 8 0 8 8 0 0 0 % L
% Met: 0 62 0 0 0 0 0 0 0 0 0 0 16 0 0 % M
% Asn: 0 16 0 8 8 8 0 24 8 0 0 0 0 0 54 % N
% Pro: 0 0 70 8 0 0 0 8 0 0 8 0 8 77 8 % P
% Gln: 8 16 0 0 0 8 0 0 0 0 16 0 0 0 8 % Q
% Arg: 0 0 8 0 0 54 0 0 0 0 0 8 0 0 0 % R
% Ser: 8 0 0 24 0 16 16 62 0 0 8 0 8 24 0 % S
% Thr: 0 0 0 0 0 0 0 0 8 0 0 8 8 0 0 % T
% Val: 8 0 0 0 8 0 0 0 0 0 8 0 39 0 16 % V
% Trp: 62 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _