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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAT3 All Species: 5.15
Human Site: S4328 Identified Species: 9.44
UniProt: Q8TDW7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDW7 NP_001008781.2 4589 505523 S4328 E V T C F A G S N K G S N S E
Chimpanzee Pan troglodytes XP_001136982 4601 507102 R4340 L P A V S P C R S D C D S I R
Rhesus Macaque Macaca mulatta XP_001084587 4609 507875 R4348 L P A V S P C R S D C D S I R
Dog Lupus familis XP_848507 4589 505147 S4328 E V T C F A G S N K G S N S E
Cat Felis silvestris
Mouse Mus musculus Q8BNA6 4555 501992 R4294 L P A V S P C R S D C D S I R
Rat Rattus norvegicus Q8R508 4555 502069 R4294 L P A V S P C R S D C D S I R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508966 4273 469286 L4014 G A P F R E G L L C L G G L V
Chicken Gallus gallus NP_001104793 4557 501888 R4297 L P A V S P C R S D C D S I R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998132 4610 506620 K4333 S D S D S I Q K P S W D Y D Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW71 4705 524557 Y4439 S T D A D N A Y K Q E W C E Q
Honey Bee Apis mellifera XP_394631 3607 400577 N3348 T T G G L L L N S S R R V P H
Nematode Worm Caenorhab. elegans Q19319 4292 477180 L4033 S T V L E F L L K A E I V I V
Sea Urchin Strong. purpuratus XP_785422 3852 424350 N3591 D D D D P G E N D P F L P A G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 95.5 N.A. 91.9 92.3 N.A. 40 86.4 N.A. 50.6 N.A. 36 31.2 26.7 21.7
Protein Similarity: 100 98.8 98.3 98.3 N.A. 96.2 96.4 N.A. 57.6 93.3 N.A. 69.1 N.A. 54.8 46.1 46.9 39.2
P-Site Identity: 100 0 0 100 N.A. 0 0 N.A. 6.6 0 N.A. 0 N.A. 0 0 0 0
P-Site Similarity: 100 13.3 13.3 100 N.A. 13.3 13.3 N.A. 6.6 13.3 N.A. 6.6 N.A. 13.3 13.3 0 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 39 8 0 16 8 0 0 8 0 0 0 8 0 % A
% Cys: 0 0 0 16 0 0 39 0 0 8 39 0 8 0 0 % C
% Asp: 8 16 16 16 8 0 0 0 8 39 0 47 0 8 0 % D
% Glu: 16 0 0 0 8 8 8 0 0 0 16 0 0 8 16 % E
% Phe: 0 0 0 8 16 8 0 0 0 0 8 0 0 0 0 % F
% Gly: 8 0 8 8 0 8 24 0 0 0 16 8 8 0 8 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 8 0 47 0 % I
% Lys: 0 0 0 0 0 0 0 8 16 16 0 0 0 0 0 % K
% Leu: 39 0 0 8 8 8 16 16 8 0 8 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 16 16 0 0 0 16 0 0 % N
% Pro: 0 39 8 0 8 39 0 0 8 8 0 0 8 8 0 % P
% Gln: 0 0 0 0 0 0 8 0 0 8 0 0 0 0 8 % Q
% Arg: 0 0 0 0 8 0 0 39 0 0 8 8 0 0 39 % R
% Ser: 24 0 8 0 47 0 0 16 47 16 0 16 39 16 0 % S
% Thr: 8 24 16 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 16 8 39 0 0 0 0 0 0 0 0 16 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _