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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAT3
All Species:
6.67
Human Site:
S4245
Identified Species:
12.22
UniProt:
Q8TDW7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDW7
NP_001008781.2
4589
505523
S4245
T
P
C
F
Q
S
D
S
R
S
N
L
D
K
I
Chimpanzee
Pan troglodytes
XP_001136982
4601
507102
S4259
P
F
R
N
L
R
G
S
G
D
G
R
N
V
Y
Rhesus Macaque
Macaca mulatta
XP_001084587
4609
507875
S4267
P
F
R
N
L
R
G
S
G
D
G
R
N
V
Y
Dog
Lupus familis
XP_848507
4589
505147
S4245
T
P
C
F
Q
G
D
S
R
S
N
L
D
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BNA6
4555
501992
R4212
G
I
P
F
R
S
L
R
A
G
D
G
R
N
V
Rat
Rattus norvegicus
Q8R508
4555
502069
R4212
G
I
P
F
R
S
L
R
A
G
D
G
R
N
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508966
4273
469286
L3933
T
R
Q
S
H
A
V
L
L
S
V
N
G
T
E
Chicken
Gallus gallus
NP_001104793
4557
501888
S4216
Q
F
K
N
I
R
N
S
G
D
S
R
N
I
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998132
4610
506620
L4245
R
P
Y
F
D
A
K
L
N
R
N
I
Y
S
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VW71
4705
524557
K4344
D
K
N
K
S
S
Y
K
E
A
N
L
N
S
L
Honey Bee
Apis mellifera
XP_394631
3607
400577
N3267
S
A
G
D
E
L
E
N
F
P
P
D
Y
L
R
Nematode Worm
Caenorhab. elegans
Q19319
4292
477180
N3952
I
Q
C
I
P
F
Y
N
D
Y
L
C
K
C
P
Sea Urchin
Strong. purpuratus
XP_785422
3852
424350
Q3510
N
M
E
P
E
I
N
Q
F
E
V
L
S
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
97.9
95.5
N.A.
91.9
92.3
N.A.
40
86.4
N.A.
50.6
N.A.
36
31.2
26.7
21.7
Protein Similarity:
100
98.8
98.3
98.3
N.A.
96.2
96.4
N.A.
57.6
93.3
N.A.
69.1
N.A.
54.8
46.1
46.9
39.2
P-Site Identity:
100
6.6
6.6
86.6
N.A.
13.3
13.3
N.A.
13.3
6.6
N.A.
20
N.A.
20
0
6.6
6.6
P-Site Similarity:
100
13.3
13.3
93.3
N.A.
33.3
33.3
N.A.
20
26.6
N.A.
33.3
N.A.
40
26.6
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
16
0
0
16
8
0
0
0
0
0
% A
% Cys:
0
0
24
0
0
0
0
0
0
0
0
8
0
8
0
% C
% Asp:
8
0
0
8
8
0
16
0
8
24
16
8
16
0
8
% D
% Glu:
0
0
8
0
16
0
8
0
8
8
0
0
0
0
8
% E
% Phe:
0
24
0
39
0
8
0
0
16
0
0
0
0
0
0
% F
% Gly:
16
0
8
0
0
8
16
0
24
16
16
16
8
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
8
8
8
0
0
0
0
0
8
0
8
8
% I
% Lys:
0
8
8
8
0
0
8
8
0
0
0
0
8
16
0
% K
% Leu:
0
0
0
0
16
8
16
16
8
0
8
31
0
8
16
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
24
0
0
16
16
8
0
31
8
31
16
0
% N
% Pro:
16
24
16
8
8
0
0
0
0
8
8
0
0
0
8
% P
% Gln:
8
8
8
0
16
0
0
8
0
0
0
0
0
0
8
% Q
% Arg:
8
8
16
0
16
24
0
16
16
8
0
24
16
0
8
% R
% Ser:
8
0
0
8
8
31
0
39
0
24
8
0
8
24
0
% S
% Thr:
24
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
8
0
0
0
16
0
0
16
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
16
0
0
8
0
0
16
0
24
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _