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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPR119
All Species:
7.88
Human Site:
Y291
Identified Species:
17.33
UniProt:
Q8TDV5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDV5
NP_848566.1
335
36889
Y291
K
E
V
R
L
Q
L
Y
H
M
A
L
G
V
K
Chimpanzee
Pan troglodytes
Q5IS65
440
46934
F334
F
K
R
A
L
G
R
F
L
P
C
P
R
C
P
Rhesus Macaque
Macaca mulatta
Q28509
415
46453
L339
F
R
I
A
F
Q
E
L
L
C
L
R
R
S
S
Dog
Lupus familis
XP_549255
335
36665
Y291
K
E
V
Q
Q
Q
L
Y
E
M
V
L
G
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q7TQP3
335
36976
Y291
R
E
V
R
Q
Q
L
Y
H
M
A
L
G
V
K
Rat
Rattus norvegicus
Q7TQN8
468
51668
C291
R
E
V
R
Q
Q
L
C
H
M
A
L
G
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
O13076
340
37753
D296
I
Y
A
Y
R
I
R
D
F
R
Y
T
F
H
K
Frog
Xenopus laevis
O42574
385
43291
L338
F
R
K
A
F
K
R
L
L
C
C
P
K
K
A
Zebra Danio
Brachydanio rerio
XP_001337269
376
42415
A326
D
Q
I
C
E
L
F
A
Y
I
K
A
G
F
C
Tiger Blowfish
Takifugu rubipres
NP_001027835
393
43445
A313
K
E
V
R
L
Q
L
A
A
M
F
S
C
F
T
Fruit Fly
Dros. melanogaster
Q4LBB9
536
60360
R477
R
D
F
R
E
A
F
R
N
T
L
L
C
L
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
23.6
25.5
84.1
N.A.
82
55.1
N.A.
N.A.
25.5
22.6
36.9
38.1
20.1
N.A.
N.A.
N.A.
Protein Similarity:
100
37
41.4
89.5
N.A.
88.3
63
N.A.
N.A.
45.2
40.5
55.3
54.9
33.5
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
73.3
N.A.
86.6
66.6
N.A.
N.A.
6.6
0
6.6
53.3
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
13.3
80
N.A.
93.3
80
N.A.
N.A.
6.6
6.6
33.3
53.3
40
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
28
0
10
0
19
10
0
28
10
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
10
0
19
19
0
19
10
10
% C
% Asp:
10
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% D
% Glu:
0
46
0
0
19
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
28
0
10
0
19
0
19
10
10
0
10
0
10
19
10
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
0
46
0
0
% G
% His:
0
0
0
0
0
0
0
0
28
0
0
0
0
10
0
% H
% Ile:
10
0
19
0
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
28
10
10
0
0
10
0
0
0
0
10
0
10
10
37
% K
% Leu:
0
0
0
0
28
10
46
19
28
0
19
46
0
19
10
% L
% Met:
0
0
0
0
0
0
0
0
0
46
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
19
0
0
10
% P
% Gln:
0
10
0
10
28
55
0
0
0
0
0
0
0
0
0
% Q
% Arg:
28
19
10
46
10
0
28
10
0
10
0
10
19
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
10
% T
% Val:
0
0
46
0
0
0
0
0
0
0
10
0
0
28
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
10
0
0
0
28
10
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _