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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRIX1
All Species:
20.61
Human Site:
Y337
Identified Species:
37.78
UniProt:
Q8TDN6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.42
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN6
NP_060791.3
353
41401
Y337
K
A
R
K
K
R
I
Y
K
R
Q
R
K
M
K
Chimpanzee
Pan troglodytes
XP_517812
327
38274
Y311
K
A
R
K
K
R
I
Y
K
R
Q
R
K
M
K
Rhesus Macaque
Macaca mulatta
XP_001089767
353
41393
Y337
K
A
R
K
K
R
I
Y
K
R
Q
R
K
M
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCA5
353
41223
Y337
K
A
R
K
R
R
I
Y
K
R
H
R
K
L
Q
Rat
Rattus norvegicus
Q4QQT6
352
41096
Y336
K
A
R
K
R
R
I
Y
K
R
H
R
K
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509107
399
46238
T382
K
K
K
K
K
L
H
T
R
Q
R
K
M
L
K
Chicken
Gallus gallus
NP_001026620
349
40314
R334
V
K
D
K
R
K
P
R
K
I
Q
R
K
K
Q
Frog
Xenopus laevis
Q8UVY2
339
39364
K323
P
A
P
K
P
K
M
K
R
K
D
K
Q
F
K
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZE6
359
41600
Q339
K
I
K
E
K
Q
L
Q
A
V
K
D
V
I
E
Honey Bee
Apis mellifera
XP_001119973
317
37427
Q302
L
E
K
A
I
E
L
Q
Q
K
E
T
K
N
I
Nematode Worm
Caenorhab. elegans
P34524
352
40215
R337
T
A
Q
I
E
K
R
R
V
R
K
K
K
S
Q
Sea Urchin
Strong. purpuratus
XP_001203643
258
30016
K243
D
E
V
F
H
T
I
K
P
E
D
A
K
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08235
291
33559
K273
A
A
V
E
R
K
I
K
R
R
E
N
V
L
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
98.3
N.A.
N.A.
91.7
91.2
N.A.
69.4
74.7
72.8
N.A.
N.A.
48.1
48.1
39.3
43.9
Protein Similarity:
100
88.6
98.3
N.A.
N.A.
94.9
94.6
N.A.
77.6
82.4
81.8
N.A.
N.A.
66
64
62.6
56
P-Site Identity:
100
100
100
N.A.
N.A.
73.3
73.3
N.A.
26.6
33.3
20
N.A.
N.A.
13.3
6.6
20
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
66.6
53.3
60
N.A.
N.A.
60
40
60
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
62
0
8
0
0
0
0
8
0
0
8
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
0
0
0
0
0
16
8
0
0
0
% D
% Glu:
0
16
0
16
8
8
0
0
0
8
16
0
0
0
8
% E
% Phe:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
16
0
0
0
0
% H
% Ile:
0
8
0
8
8
0
54
0
0
8
0
0
0
8
8
% I
% Lys:
54
16
24
62
39
31
0
24
47
16
16
24
70
8
39
% K
% Leu:
8
0
0
0
0
8
16
0
0
0
0
0
0
31
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
8
24
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
8
0
8
0
8
0
8
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
8
0
16
8
8
31
0
8
0
31
% Q
% Arg:
0
0
39
0
31
39
8
16
24
54
8
47
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
8
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% T
% Val:
8
0
16
0
0
0
0
0
8
8
0
0
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _