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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRIX1
All Species:
36.06
Human Site:
Y254
Identified Species:
66.11
UniProt:
Q8TDN6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN6
NP_060791.3
353
41401
Y254
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Chimpanzee
Pan troglodytes
XP_517812
327
38274
Y228
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Rhesus Macaque
Macaca mulatta
XP_001089767
353
41393
Y254
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCA5
353
41223
Y254
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Rat
Rattus norvegicus
Q4QQT6
352
41096
Y253
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509107
399
46238
Y298
S
F
G
G
P
T
L
Y
E
N
P
K
Y
Q
S
Chicken
Gallus gallus
NP_001026620
349
40314
Y252
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Frog
Xenopus laevis
Q8UVY2
339
39364
Y247
S
F
G
G
P
T
L
Y
E
N
P
H
Y
Q
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZE6
359
41600
W246
S
F
T
G
K
T
I
W
E
N
P
D
Y
V
S
Honey Bee
Apis mellifera
XP_001119973
317
37427
K227
R
F
V
L
N
P
I
K
I
F
T
D
S
F
G
Nematode Worm
Caenorhab. elegans
P34524
352
40215
Y258
S
F
E
G
A
V
L
Y
D
N
P
N
Y
V
S
Sea Urchin
Strong. purpuratus
XP_001203643
258
30016
I177
L
V
L
N
L
I
K
I
F
S
G
S
F
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08235
291
33559
Y203
S
T
K
N
K
E
E
Y
E
D
G
E
E
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
98.3
N.A.
N.A.
91.7
91.2
N.A.
69.4
74.7
72.8
N.A.
N.A.
48.1
48.1
39.3
43.9
Protein Similarity:
100
88.6
98.3
N.A.
N.A.
94.9
94.6
N.A.
77.6
82.4
81.8
N.A.
N.A.
66
64
62.6
56
P-Site Identity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
100
100
N.A.
N.A.
60
6.6
60
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
100
100
N.A.
N.A.
73.3
13.3
73.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
8
0
16
0
8
0
% D
% Glu:
0
0
8
0
0
8
8
0
77
0
0
8
8
0
0
% E
% Phe:
0
85
0
0
0
0
0
0
8
8
0
0
8
8
0
% F
% Gly:
0
0
62
77
0
0
0
0
0
0
16
0
0
0
16
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
54
0
0
0
% H
% Ile:
0
0
0
0
0
8
16
8
8
0
0
0
0
0
8
% I
% Lys:
0
0
8
0
16
0
8
8
0
0
0
8
0
0
0
% K
% Leu:
8
0
8
8
8
0
70
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
8
0
0
0
0
77
0
8
0
0
0
% N
% Pro:
0
0
0
0
62
8
0
0
0
0
77
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
62
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
85
0
0
0
0
0
0
0
0
8
0
8
8
0
77
% S
% Thr:
0
8
8
0
0
70
0
0
0
0
8
0
0
0
0
% T
% Val:
0
8
8
0
0
8
0
0
0
0
0
0
0
16
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
0
0
77
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _