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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRIX1
All Species:
34.85
Human Site:
Y178
Identified Species:
63.89
UniProt:
Q8TDN6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN6
NP_060791.3
353
41401
Y178
A
F
D
E
L
P
H
Y
A
L
L
K
E
L
L
Chimpanzee
Pan troglodytes
XP_517812
327
38274
Y152
A
F
D
E
L
P
H
Y
A
L
L
K
E
L
L
Rhesus Macaque
Macaca mulatta
XP_001089767
353
41393
Y178
A
F
D
E
L
P
H
Y
A
L
L
K
E
L
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCA5
353
41223
Y178
A
F
D
D
L
P
H
Y
A
L
L
K
E
F
L
Rat
Rattus norvegicus
Q4QQT6
352
41096
Y177
A
F
D
D
L
P
H
Y
A
L
L
K
E
F
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509107
399
46238
Y222
M
F
D
K
E
P
Q
Y
A
L
L
K
E
L
F
Chicken
Gallus gallus
NP_001026620
349
40314
Y176
T
F
D
K
E
P
H
Y
A
L
L
K
E
L
F
Frog
Xenopus laevis
Q8UVY2
339
39364
Y171
A
F
D
R
E
P
Q
Y
A
L
L
K
E
L
L
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VZE6
359
41600
L170
K
F
D
E
L
P
H
L
K
L
L
K
E
L
F
Honey Bee
Apis mellifera
XP_001119973
317
37427
Y163
H
F
N
T
K
L
H
Y
S
L
L
K
E
L
L
Nematode Worm
Caenorhab. elegans
P34524
352
40215
L181
A
F
D
K
K
P
Q
L
K
L
I
K
A
V
L
Sea Urchin
Strong. purpuratus
XP_001203643
258
30016
S124
F
L
L
F
Q
I
F
S
T
P
Y
L
H
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08235
291
33559
Y149
R
F
E
S
S
P
H
Y
Q
L
I
K
E
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.2
98.3
N.A.
N.A.
91.7
91.2
N.A.
69.4
74.7
72.8
N.A.
N.A.
48.1
48.1
39.3
43.9
Protein Similarity:
100
88.6
98.3
N.A.
N.A.
94.9
94.6
N.A.
77.6
82.4
81.8
N.A.
N.A.
66
64
62.6
56
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
66.6
73.3
80
N.A.
N.A.
73.3
60
46.6
0
P-Site Similarity:
100
100
100
N.A.
N.A.
93.3
93.3
N.A.
73.3
80
80
N.A.
N.A.
73.3
73.3
66.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
34.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
50.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
54
0
0
0
0
0
0
0
62
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
77
16
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
31
24
0
0
0
0
0
0
0
85
0
0
% E
% Phe:
8
93
0
8
0
0
8
0
0
0
0
0
0
16
24
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
0
0
70
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
16
0
0
0
0
% I
% Lys:
8
0
0
24
16
0
0
0
16
0
0
93
0
0
8
% K
% Leu:
0
8
8
0
47
8
0
16
0
93
77
8
0
70
70
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
85
0
0
0
8
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
0
24
0
8
0
0
0
0
0
0
% Q
% Arg:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
8
8
0
0
8
8
0
0
0
0
0
0
% S
% Thr:
8
0
0
8
0
0
0
0
8
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
77
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _