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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES1
All Species:
10.3
Human Site:
T229
Identified Species:
20.61
UniProt:
Q8TDN4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN4
NP_001094089.1
633
67599
T229
A
A
F
L
G
S
G
T
P
G
S
G
S
G
S
Chimpanzee
Pan troglodytes
XP_512059
702
76038
T298
A
A
F
L
S
S
G
T
P
G
S
G
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
K69
C
A
P
A
Q
R
T
K
H
T
S
G
S
P
R
Dog
Lupus familis
XP_855204
432
47740
K101
I
S
G
S
P
R
H
K
G
L
K
K
T
H
F
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ1
568
61363
T190
A
S
F
L
G
S
G
T
P
G
S
T
S
G
S
Rat
Rattus norvegicus
NP_001100874
517
56679
S176
N
Y
C
A
L
E
Q
S
G
Q
G
G
S
T
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509331
207
23163
Chicken
Gallus gallus
XP_001232075
374
42871
A42
L
E
D
I
E
E
N
A
P
L
R
R
C
R
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099135
525
58654
L175
L
Q
R
S
R
R
R
L
I
S
Q
R
S
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
A269
L
G
S
G
G
G
V
A
G
G
A
G
S
K
L
Honey Bee
Apis mellifera
XP_623648
562
63688
T171
R
I
T
H
Q
T
S
T
L
S
E
D
I
K
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
I82
S
P
P
A
G
F
Q
I
P
V
A
K
T
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
35.8
37.2
N.A.
76.1
72.8
N.A.
30.3
53.5
N.A.
62.4
N.A.
29.9
28.5
N.A.
28.2
Protein Similarity:
100
74.7
45
45.5
N.A.
79.7
75
N.A.
31.6
56.5
N.A.
69.9
N.A.
44
45.9
N.A.
44.5
P-Site Identity:
100
93.3
26.6
0
N.A.
86.6
13.3
N.A.
0
6.6
N.A.
6.6
N.A.
26.6
6.6
N.A.
13.3
P-Site Similarity:
100
93.3
26.6
13.3
N.A.
93.3
26.6
N.A.
0
20
N.A.
6.6
N.A.
33.3
13.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
25
0
25
0
0
0
17
0
0
17
0
0
0
0
% A
% Cys:
9
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
9
0
0
9
17
0
0
0
0
9
0
0
0
0
% E
% Phe:
0
0
25
0
0
9
0
0
0
0
0
0
0
9
9
% F
% Gly:
0
9
9
9
34
9
25
0
25
34
9
42
0
25
0
% G
% His:
0
0
0
9
0
0
9
0
9
0
0
0
0
9
9
% H
% Ile:
9
9
0
9
0
0
0
9
9
0
0
0
9
0
0
% I
% Lys:
0
0
0
0
0
0
0
17
0
0
9
17
0
17
0
% K
% Leu:
25
0
0
25
9
0
0
9
9
17
0
0
0
0
17
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
17
0
9
0
0
0
42
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
17
0
17
0
0
9
9
0
0
0
0
% Q
% Arg:
9
0
9
0
9
25
9
0
0
0
9
17
0
9
17
% R
% Ser:
9
17
9
17
9
25
9
9
0
17
34
0
59
9
25
% S
% Thr:
0
0
9
0
0
9
9
34
0
9
0
9
17
9
17
% T
% Val:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _