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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES1
All Species:
7.88
Human Site:
S434
Identified Species:
15.76
UniProt:
Q8TDN4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN4
NP_001094089.1
633
67599
S434
N
L
S
H
R
S
L
S
I
G
R
A
S
G
T
Chimpanzee
Pan troglodytes
XP_512059
702
76038
S503
N
L
S
H
R
S
L
S
I
G
R
A
S
G
T
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
M266
P
S
D
L
K
K
D
M
N
E
T
F
R
E
K
Dog
Lupus familis
XP_855204
432
47740
M298
P
S
D
L
K
K
D
M
N
E
T
F
R
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ1
568
61363
D398
D
Y
D
P
N
L
L
D
D
P
Q
W
P
C
G
Rat
Rattus norvegicus
NP_001100874
517
56679
S376
V
I
D
Y
V
K
P
S
D
L
K
K
D
M
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509331
207
23163
L73
Q
S
T
G
A
G
S
L
R
E
I
I
G
L
E
Chicken
Gallus gallus
XP_001232075
374
42871
N240
S
D
L
K
K
D
M
N
E
T
F
K
E
K
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099135
525
58654
S384
V
I
E
Y
V
K
P
S
D
L
K
K
D
M
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
P519
N
S
A
T
S
P
T
P
D
M
K
L
D
M
D
Honey Bee
Apis mellifera
XP_623648
562
63688
S370
T
P
E
S
P
P
L
S
F
N
T
D
S
K
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
E279
K
P
S
E
L
K
K
E
L
N
N
K
F
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
35.8
37.2
N.A.
76.1
72.8
N.A.
30.3
53.5
N.A.
62.4
N.A.
29.9
28.5
N.A.
28.2
Protein Similarity:
100
74.7
45
45.5
N.A.
79.7
75
N.A.
31.6
56.5
N.A.
69.9
N.A.
44
45.9
N.A.
44.5
P-Site Identity:
100
100
0
0
N.A.
6.6
6.6
N.A.
0
0
N.A.
6.6
N.A.
6.6
20
N.A.
6.6
P-Site Similarity:
100
100
6.6
6.6
N.A.
20
26.6
N.A.
6.6
26.6
N.A.
26.6
N.A.
20
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
0
0
0
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
9
9
34
0
0
9
17
9
34
0
0
9
25
0
9
% D
% Glu:
0
0
17
9
0
0
0
9
9
25
0
0
9
17
17
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
9
17
9
0
9
% F
% Gly:
0
0
0
9
0
9
0
0
0
17
0
0
9
17
9
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
17
0
0
0
0
0
0
17
0
9
9
0
0
0
% I
% Lys:
9
0
0
9
25
42
9
0
0
0
25
34
0
17
17
% K
% Leu:
0
17
9
17
9
9
34
9
9
17
0
9
0
9
0
% L
% Met:
0
0
0
0
0
0
9
17
0
9
0
0
0
25
0
% M
% Asn:
25
0
0
0
9
0
0
9
17
17
9
0
0
0
17
% N
% Pro:
17
17
0
9
9
17
17
9
0
9
0
0
9
0
0
% P
% Gln:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
17
0
0
0
9
0
17
0
17
9
0
% R
% Ser:
9
34
25
9
9
17
9
42
0
0
0
0
25
0
0
% S
% Thr:
9
0
9
9
0
0
9
0
0
9
25
0
0
0
17
% T
% Val:
17
0
0
0
17
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
9
0
17
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _