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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CABLES1 All Species: 9.09
Human Site: S311 Identified Species: 18.18
UniProt: Q8TDN4 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDN4 NP_001094089.1 633 67599 S311 L R R C R T L S G S P R P K N
Chimpanzee Pan troglodytes XP_512059 702 76038 S380 L R R C R T L S G S P R P K N
Rhesus Macaque Macaca mulatta XP_001115094 400 44686 E151 S E M V F E L E G V E L G A D
Dog Lupus familis XP_855204 432 47740 K183 V E L G A D G K V V S Y A K F
Cat Felis silvestris
Mouse Mus musculus Q9ESJ1 568 61363 S272 L R R C R T L S G S P R P K N
Rat Rattus norvegicus NP_001100874 517 56679 A258 L D G G R Q S A G A M S L K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509331 207 23163
Chicken Gallus gallus XP_001232075 374 42871 I124 G V C L K E I I G L E G V E L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001099135 525 58654 A257 S Q T G D V K A E S G R Q R H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610890 717 79307 A351 L T P A G N Y A G S F R N S L
Honey Bee Apis mellifera XP_623648 562 63688 V253 N K R V P F L V F S A L P Y N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790638 413 47121 V164 L D G V E L G V E G T V V S F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 71.5 35.8 37.2 N.A. 76.1 72.8 N.A. 30.3 53.5 N.A. 62.4 N.A. 29.9 28.5 N.A. 28.2
Protein Similarity: 100 74.7 45 45.5 N.A. 79.7 75 N.A. 31.6 56.5 N.A. 69.9 N.A. 44 45.9 N.A. 44.5
P-Site Identity: 100 100 13.3 6.6 N.A. 100 26.6 N.A. 0 6.6 N.A. 13.3 N.A. 26.6 33.3 N.A. 6.6
P-Site Similarity: 100 100 20 13.3 N.A. 100 40 N.A. 0 26.6 N.A. 40 N.A. 33.3 40 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 25 0 9 9 0 9 9 0 % A
% Cys: 0 0 9 25 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 9 9 0 0 0 0 0 0 0 0 9 % D
% Glu: 0 17 0 0 9 17 0 9 17 0 17 0 0 9 9 % E
% Phe: 0 0 0 0 9 9 0 0 9 0 9 0 0 0 17 % F
% Gly: 9 0 17 25 9 0 17 0 59 9 9 9 9 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % H
% Ile: 0 0 0 0 0 0 9 9 0 0 0 0 0 0 0 % I
% Lys: 0 9 0 0 9 0 9 9 0 0 0 0 0 42 0 % K
% Leu: 50 0 9 9 0 9 42 0 0 9 0 17 9 0 17 % L
% Met: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % M
% Asn: 9 0 0 0 0 9 0 0 0 0 0 0 9 0 34 % N
% Pro: 0 0 9 0 9 0 0 0 0 0 25 0 34 0 0 % P
% Gln: 0 9 0 0 0 9 0 0 0 0 0 0 9 0 0 % Q
% Arg: 0 25 34 0 34 0 0 0 0 0 0 42 0 9 0 % R
% Ser: 17 0 0 0 0 0 9 25 0 50 9 9 0 17 0 % S
% Thr: 0 9 9 0 0 25 0 0 0 0 9 0 0 0 0 % T
% Val: 9 9 0 25 0 9 0 17 9 17 0 9 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 9 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _