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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CABLES1
All Species:
10
Human Site:
S271
Identified Species:
20
UniProt:
Q8TDN4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TDN4
NP_001094089.1
633
67599
S271
E
Q
P
G
Q
G
G
S
T
S
A
F
E
Q
L
Chimpanzee
Pan troglodytes
XP_512059
702
76038
S340
E
Q
P
G
Q
G
G
S
T
S
A
F
E
Q
L
Rhesus Macaque
Macaca mulatta
XP_001115094
400
44686
A111
A
K
R
S
L
C
A
A
F
S
V
L
P
Y
G
Dog
Lupus familis
XP_855204
432
47740
G143
S
V
L
P
Y
G
E
G
L
R
V
S
D
L
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9ESJ1
568
61363
S232
E
Q
S
G
Q
G
G
S
T
S
A
L
E
Q
L
Rat
Rattus norvegicus
NP_001100874
517
56679
R218
N
A
P
L
R
R
C
R
T
L
S
G
S
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509331
207
23163
Chicken
Gallus gallus
XP_001232075
374
42871
R84
R
I
V
L
I
S
S
R
R
S
F
C
S
I
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001099135
525
58654
N217
K
K
V
H
F
I
K
N
T
R
Q
H
D
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610890
717
79307
S311
A
P
G
M
R
V
G
S
N
S
S
I
A
M
G
Honey Bee
Apis mellifera
XP_623648
562
63688
N213
N
V
Q
C
S
S
A
N
S
G
I
I
P
E
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790638
413
47121
I124
T
R
R
S
Q
L
G
I
Y
R
K
N
S
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
71.5
35.8
37.2
N.A.
76.1
72.8
N.A.
30.3
53.5
N.A.
62.4
N.A.
29.9
28.5
N.A.
28.2
Protein Similarity:
100
74.7
45
45.5
N.A.
79.7
75
N.A.
31.6
56.5
N.A.
69.9
N.A.
44
45.9
N.A.
44.5
P-Site Identity:
100
100
6.6
6.6
N.A.
86.6
13.3
N.A.
0
6.6
N.A.
6.6
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
100
20
13.3
N.A.
86.6
26.6
N.A.
0
6.6
N.A.
33.3
N.A.
33.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
0
0
17
9
0
0
25
0
9
0
9
% A
% Cys:
0
0
0
9
0
9
9
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% D
% Glu:
25
0
0
0
0
0
9
0
0
0
0
0
25
17
0
% E
% Phe:
0
0
0
0
9
0
0
0
9
0
9
17
0
0
9
% F
% Gly:
0
0
9
25
0
34
42
9
0
9
0
9
0
0
17
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
9
0
0
9
9
0
9
0
0
9
17
0
9
0
% I
% Lys:
9
17
0
0
0
0
9
0
0
0
9
0
0
0
0
% K
% Leu:
0
0
9
17
9
9
0
0
9
9
0
17
0
9
25
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
17
0
% M
% Asn:
17
0
0
0
0
0
0
17
9
0
0
9
0
0
0
% N
% Pro:
0
9
25
9
0
0
0
0
0
0
0
0
17
9
0
% P
% Gln:
0
25
9
0
34
0
0
0
0
0
9
0
0
25
0
% Q
% Arg:
9
9
17
0
17
9
0
17
9
25
0
0
0
0
25
% R
% Ser:
9
0
9
17
9
17
9
34
9
50
17
9
25
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
42
0
0
0
0
0
0
% T
% Val:
0
17
17
0
0
9
0
0
0
0
17
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
9
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _