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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PHOSPHO1 All Species: 26.36
Human Site: S246 Identified Species: 58
UniProt: Q8TCT1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCT1 NP_001137276.1 267 29713 S246 E P S S F R A S V V P W E T A
Chimpanzee Pan troglodytes XP_001172554 267 29678 S246 E P S S F R A S V V P W E T A
Rhesus Macaque Macaca mulatta XP_001092436 267 29648 S246 E P S S F R A S V V P W E T A
Dog Lupus familis XP_548189 267 29587 S246 E P S S F R A S V V P W E T A
Cat Felis silvestris
Mouse Mus musculus Q8R2H9 267 29893 H246 E P S S F R A H V V P W E T A
Rat Rattus norvegicus Q66HC4 241 27608 S221 N L E P M A S S I V V W S S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517222 347 38864 A326 Q P G A F R A A V V P W E S A
Chicken Gallus gallus O73884 268 30424 T246 Q P G T F Q A T V V P W E S A
Frog Xenopus laevis NP_001090404 238 26758 A218 D D A L V D S A I S V W S T G
Zebra Danio Brachydanio rerio Q6DBV4 279 31385 S258 K P G E F K A S V V P W K S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796940 255 28970 T235 N D E C I K A T V L P W D T A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.1 95.8 N.A. 92.8 37 N.A. 58.5 59.7 37.4 49.8 N.A. N.A. N.A. N.A. 32.2
Protein Similarity: 100 100 98.5 98.1 N.A. 95.8 58.7 N.A. 64.2 74.6 59.1 63.4 N.A. N.A. N.A. N.A. 53.1
P-Site Identity: 100 100 100 100 N.A. 93.3 20 N.A. 66.6 60 13.3 53.3 N.A. N.A. N.A. N.A. 40
P-Site Similarity: 100 100 100 100 N.A. 93.3 40 N.A. 93.3 93.3 46.6 80 N.A. N.A. N.A. N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 82 19 0 0 0 0 0 0 73 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 19 0 0 0 10 0 0 0 0 0 0 10 0 0 % D
% Glu: 46 0 19 10 0 0 0 0 0 0 0 0 64 0 0 % E
% Phe: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 28 0 0 0 0 0 0 0 0 0 0 0 28 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 0 0 19 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 19 0 0 0 0 0 0 10 0 0 % K
% Leu: 0 10 0 10 0 0 0 0 0 10 0 0 0 0 0 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 73 0 10 0 0 0 0 0 0 82 0 0 0 0 % P
% Gln: 19 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 55 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 46 46 0 0 19 55 0 10 0 0 19 37 0 % S
% Thr: 0 0 0 10 0 0 0 19 0 0 0 0 0 64 0 % T
% Val: 0 0 0 0 10 0 0 0 82 82 19 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _