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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FBXO25
All Species:
27.27
Human Site:
Y124
Identified Species:
66.67
UniProt:
Q8TCJ0
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCJ0
NP_036305.2
367
43313
Y124
Q
D
I
R
R
F
N
Y
V
V
K
L
L
Q
L
Chimpanzee
Pan troglodytes
XP_001142528
341
40442
A115
N
R
L
D
F
S
S
A
I
Q
D
I
R
R
F
Rhesus Macaque
Macaca mulatta
XP_001094917
367
43275
Y124
Q
D
I
R
R
F
N
Y
V
V
K
L
L
Q
L
Dog
Lupus familis
XP_849788
367
43366
Y124
Q
D
I
R
R
F
T
Y
V
V
K
L
L
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2Y6
357
41807
Y123
Q
D
I
R
R
F
T
Y
V
V
K
L
L
Q
L
Rat
Rattus norvegicus
Q641X7
357
41966
Y123
Q
D
I
R
R
F
T
Y
V
V
K
L
L
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516914
350
41062
S122
I
A
K
S
Q
L
T
S
L
S
G
A
A
Q
K
Chicken
Gallus gallus
XP_419924
370
43376
Y127
Q
D
I
R
R
F
N
Y
V
V
K
L
L
Q
L
Frog
Xenopus laevis
NP_001085052
351
41683
L124
Y
V
V
K
L
L
Q
L
I
A
K
S
Q
L
T
Zebra Danio
Brachydanio rerio
NP_991287
356
41837
Y122
Q
D
V
R
R
F
N
Y
V
V
K
L
L
Q
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
99.7
91.5
N.A.
86.3
86.3
N.A.
82.5
83.7
70
74.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.6
99.7
95.9
N.A.
91.8
91.8
N.A.
88.5
91.8
83.3
83.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
0
100
93.3
N.A.
93.3
93.3
N.A.
6.6
100
6.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
93.3
93.3
N.A.
20
100
26.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
10
0
10
0
10
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
70
0
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
70
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
60
0
0
0
0
0
20
0
0
10
0
0
0
% I
% Lys:
0
0
10
10
0
0
0
0
0
0
80
0
0
0
10
% K
% Leu:
0
0
10
0
10
20
0
10
10
0
0
70
70
10
70
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
40
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
70
0
0
0
10
0
10
0
0
10
0
0
10
80
0
% Q
% Arg:
0
10
0
70
70
0
0
0
0
0
0
0
10
10
0
% R
% Ser:
0
0
0
10
0
10
10
10
0
10
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
0
40
0
0
0
0
0
0
0
10
% T
% Val:
0
10
20
0
0
0
0
0
70
70
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _