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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CPT1C All Species: 9.09
Human Site: S370 Identified Species: 20
UniProt: Q8TCG5 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.4
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCG5 NP_001129524.1 803 90989 S370 Q R I L D D P S P A C P H E E
Chimpanzee Pan troglodytes XP_001173820 773 88331 R352 V W L Y H D G R L L K P R E M
Rhesus Macaque Macaca mulatta XP_001101846 773 88366 R352 V W L Y H D G R L L K P R E M
Dog Lupus familis XP_533614 803 91211 S370 Q R I L D D P S P A C P Q E E
Cat Felis silvestris
Mouse Mus musculus Q8BGD5 798 90011 S369 Q D I L D D P S P A C P L E E
Rat Rattus norvegicus P32198 773 88107 R352 V W L Y H D G R L L R P R E L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90YJ9 640 72605 K230 T Q L R K I A K M A E N E E E
Frog Xenopus laevis Q7ZXE1 659 74538 R249 G R H L L V L R K G N F Y V F
Zebra Danio Brachydanio rerio B2ZGJ1 637 71821 A227 L E R I R K M A D I E E E R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P32756 627 71299 Y217 V S Y A D V E Y Q L A Q I E E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32796 670 77223 D260 F Y K L M T H D G N D K P L S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.1 53.4 90.2 N.A. 83.3 53.5 N.A. N.A. 21.7 24 22.5 N.A. N.A. N.A. 20.1 N.A.
Protein Similarity: 100 70.4 70.7 94.2 N.A. 89.4 70.2 N.A. N.A. 40.5 39.8 38.3 N.A. N.A. N.A. 36.1 N.A.
P-Site Identity: 100 20 20 93.3 N.A. 86.6 20 N.A. N.A. 20 13.3 0 N.A. N.A. N.A. 20 N.A.
P-Site Similarity: 100 26.6 26.6 93.3 N.A. 86.6 26.6 N.A. N.A. 33.3 20 20 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 10 10 0 37 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 28 0 0 0 0 % C
% Asp: 0 10 0 0 37 55 0 10 10 0 10 0 0 0 0 % D
% Glu: 0 10 0 0 0 0 10 0 0 0 19 10 19 73 46 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % F
% Gly: 10 0 0 0 0 0 28 0 10 10 0 0 0 0 0 % G
% His: 0 0 10 0 28 0 10 0 0 0 0 0 10 0 0 % H
% Ile: 0 0 28 10 0 10 0 0 0 10 0 0 10 0 0 % I
% Lys: 0 0 10 0 10 10 0 10 10 0 19 10 0 0 0 % K
% Leu: 10 0 37 46 10 0 10 0 28 37 0 0 10 10 10 % L
% Met: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 19 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 10 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 28 0 28 0 0 55 10 0 0 % P
% Gln: 28 10 0 0 0 0 0 0 10 0 0 10 10 0 10 % Q
% Arg: 0 28 10 10 10 0 0 37 0 0 10 0 28 10 0 % R
% Ser: 0 10 0 0 0 0 0 28 0 0 0 0 0 0 10 % S
% Thr: 10 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % T
% Val: 37 0 0 0 0 19 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 28 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 10 28 0 0 0 10 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _