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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
43.03
Human Site:
Y134
Identified Species:
78.89
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
Y134
S
Q
G
S
S
G
S
Y
F
V
K
D
P
K
R
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
Y138
Y
Q
G
S
S
G
S
Y
F
V
K
D
P
Q
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
Y143
Y
Q
G
S
S
G
S
Y
F
V
K
D
P
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
Y122
S
Q
G
S
S
G
S
Y
F
V
K
D
S
K
R
Rat
Rattus norvegicus
Q5XIL2
477
54446
Y130
S
Q
G
S
S
G
S
Y
F
V
K
D
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
Y93
L
N
P
K
W
T
K
Y
F
H
K
V
C
C
P
Chicken
Gallus gallus
Q5ZIK0
479
53903
Y132
S
Q
G
S
S
G
S
Y
F
V
K
D
C
K
G
Frog
Xenopus laevis
Q6DCQ8
495
56331
Y144
S
Q
G
S
S
G
S
Y
F
V
K
D
P
K
G
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
Y155
S
Q
G
S
S
G
S
Y
F
V
K
D
P
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
Y129
Y
Q
G
S
S
G
S
Y
F
V
K
N
P
T
G
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
Y138
A
Q
G
S
S
G
S
Y
F
V
K
N
M
H
D
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
Y152
S
Q
G
S
S
G
S
Y
F
V
K
S
Y
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
Y175
Q
T
G
S
S
G
S
Y
F
V
Y
G
T
R
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
80
N.A.
80
N.A.
93.3
93.3
N.A.
20
86.6
93.3
93.3
N.A.
N.A.
73.3
66.6
73.3
P-Site Similarity:
100
86.6
N.A.
86.6
N.A.
93.3
93.3
N.A.
20
86.6
93.3
93.3
N.A.
N.A.
80
80
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
16
8
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
62
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% F
% Gly:
0
0
93
0
0
93
0
0
0
0
0
8
0
0
54
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
0
0
8
0
0
0
93
0
0
47
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
0
0
0
0
47
0
8
% P
% Gln:
8
85
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
24
% R
% Ser:
54
0
0
93
93
0
93
0
0
0
0
8
16
0
0
% S
% Thr:
0
8
0
0
0
8
0
0
0
0
0
0
8
16
0
% T
% Val:
0
0
0
0
0
0
0
0
0
93
0
8
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
0
0
0
0
0
0
100
0
0
8
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _