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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
28.18
Human Site:
T470
Identified Species:
51.67
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
T470
L
S
N
S
F
T
Q
T
V
N
C
R
K
P
F
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
S470
S
S
E
S
Y
T
Q
S
F
Q
S
R
K
P
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
S473
S
S
E
S
Y
T
Q
S
F
Q
S
R
K
P
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
T458
L
G
S
S
F
T
Q
T
V
H
C
R
K
P
F
Rat
Rattus norvegicus
Q5XIL2
477
54446
T466
L
G
S
S
F
T
Q
T
V
H
C
R
K
P
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
T398
L
S
N
S
N
A
F
T
Q
T
V
H
C
R
K
Chicken
Gallus gallus
Q5ZIK0
479
53903
T468
L
S
N
A
F
T
Q
T
F
H
S
R
K
P
F
Frog
Xenopus laevis
Q6DCQ8
495
56331
T484
M
S
N
A
F
T
Q
T
F
H
C
R
K
P
F
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
T490
L
G
N
A
F
T
Q
T
F
H
C
K
R
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
R455
F
S
D
T
F
T
Q
R
F
Q
N
K
S
P
F
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
A522
R
N
A
D
Y
E
E
A
P
N
Y
D
S
D
A
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
F492
I
R
H
H
S
D
S
F
T
Q
S
F
H
Q
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
A541
P
V
S
I
F
K
N
A
I
D
E
P
I
G
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
53.3
N.A.
53.3
N.A.
80
80
N.A.
33.3
73.3
73.3
60
N.A.
N.A.
40
6.6
0
P-Site Similarity:
100
66.6
N.A.
66.6
N.A.
93.3
93.3
N.A.
33.3
86.6
93.3
86.6
N.A.
N.A.
60
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
24
0
8
0
16
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
39
0
8
0
0
% C
% Asp:
0
0
8
8
0
8
0
0
0
8
0
8
0
8
0
% D
% Glu:
0
0
16
0
0
8
8
0
0
0
8
0
0
0
0
% E
% Phe:
8
0
0
0
62
0
8
8
47
0
0
8
0
0
70
% F
% Gly:
0
24
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
39
0
8
8
0
0
% H
% Ile:
8
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
8
0
0
0
0
0
16
54
0
16
% K
% Leu:
47
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
39
0
8
0
8
0
0
16
8
0
0
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
8
0
0
8
0
70
0
% P
% Gln:
0
0
0
0
0
0
70
0
8
31
0
0
0
8
0
% Q
% Arg:
8
8
0
0
0
0
0
8
0
0
0
54
8
8
0
% R
% Ser:
16
54
24
47
8
0
8
16
0
0
31
0
16
0
8
% S
% Thr:
0
0
0
8
0
70
0
54
8
8
0
0
0
0
0
% T
% Val:
0
8
0
0
0
0
0
0
24
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
24
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _