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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4K2B
All Species:
22.42
Human Site:
S452
Identified Species:
41.11
UniProt:
Q8TCG2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TCG2
NP_060793.2
481
54744
S452
P
C
V
I
V
E
R
S
Q
G
G
S
Q
G
R
Chimpanzee
Pan troglodytes
XP_001164880
481
54254
I452
L
V
Q
M
P
P
V
I
V
E
T
A
R
S
H
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543953
484
54388
I455
L
V
Q
M
P
P
V
I
V
E
T
A
R
S
H
Cat
Felis silvestris
Mouse
Mus musculus
Q8CBQ5
469
53459
S440
P
C
V
I
V
E
C
S
K
S
G
S
Q
G
R
Rat
Rattus norvegicus
Q5XIL2
477
54446
S448
P
C
V
I
V
E
C
S
K
S
G
G
Q
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513782
411
46894
S380
P
R
V
I
V
E
R
S
Q
S
G
S
Q
G
R
Chicken
Gallus gallus
Q5ZIK0
479
53903
S450
P
R
V
I
V
E
R
S
S
T
G
S
Q
G
R
Frog
Xenopus laevis
Q6DCQ8
495
56331
S466
P
R
V
V
V
E
R
S
Y
S
G
S
Q
G
R
Zebra Danio
Brachydanio rerio
Q49GP5
501
56180
S472
P
R
V
V
V
E
R
S
R
S
G
G
Q
G
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120474
466
53705
A437
P
A
V
I
V
E
K
A
K
G
N
G
A
P
R
Nematode Worm
Caenorhab. elegans
NP_508849
593
66195
V504
P
P
Q
L
M
V
E
V
K
Q
K
K
K
K
S
Sea Urchin
Strong. purpuratus
XP_801707
506
57844
N474
P
L
I
T
V
E
K
N
K
Q
D
G
S
T
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P42951
607
70198
D523
R
T
R
C
Q
V
I
D
E
K
M
Q
V
P
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.6
N.A.
58.8
N.A.
79.2
79.8
N.A.
71.7
70.6
70.7
67.4
N.A.
N.A.
54.6
40.2
53.7
Protein Similarity:
100
71.9
N.A.
71.4
N.A.
87.5
87.5
N.A.
77.7
78.3
78.7
78.2
N.A.
N.A.
70.2
53.6
66.2
P-Site Identity:
100
0
N.A.
0
N.A.
80
73.3
N.A.
86.6
80
73.3
66.6
N.A.
N.A.
46.6
6.6
20
P-Site Similarity:
100
20
N.A.
20
N.A.
86.6
80
N.A.
86.6
80
80
80
N.A.
N.A.
66.6
33.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
26.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
16
8
0
0
% A
% Cys:
0
24
0
8
0
0
16
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
70
8
0
8
16
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
16
54
31
0
54
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
8
47
0
0
8
16
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
16
0
39
8
8
8
8
8
0
% K
% Leu:
16
8
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
16
8
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% N
% Pro:
77
8
0
0
16
16
0
0
0
0
0
0
0
16
0
% P
% Gln:
0
0
24
0
8
0
0
0
16
16
0
8
54
0
0
% Q
% Arg:
8
31
8
0
0
0
39
0
8
0
0
0
16
0
62
% R
% Ser:
0
0
0
0
0
0
0
54
8
39
0
39
8
16
8
% S
% Thr:
0
8
0
8
0
0
0
0
0
8
16
0
0
8
0
% T
% Val:
0
16
62
16
70
16
16
8
16
0
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _