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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIAA1524 All Species: 17.88
Human Site: S333 Identified Species: 35.76
UniProt: Q8TCG1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TCG1 NP_065941.2 905 102185 S333 P G S A T L G S H T K C L E P
Chimpanzee Pan troglodytes XP_001151616 906 102287 S333 P G S A T L G S H T K C L E P
Rhesus Macaque Macaca mulatta XP_001101310 906 102265 S333 P G S A T L G S H T K C L E P
Dog Lupus familis XP_535731 908 102554 S335 S R N T I L G S R S K C L E P
Cat Felis silvestris
Mouse Mus musculus Q8BWY9 907 102093 S334 P S G N I L G S R P K S L E P
Rat Rattus norvegicus XP_340983 909 102425 S335 S G N N I L G S R S P K S L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509209 959 107012 G385 S G N S R L G G R P K S P D P
Chicken Gallus gallus Q5ZMJ7 909 101741 R335 L P V S G N T R F V T R S K T
Frog Xenopus laevis Q5XK92 906 101650 R335 K P G A G S G R L G P G T K S
Zebra Danio Brachydanio rerio NP_001107893 896 99448 R335 P R L Q P G T R K G V Q A R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796563 928 104857 H365 V Q R G Q E T H Q S E A F F A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P25386 1790 206434 T756 L Q T E T E S T H E N L T E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 98.7 90.9 N.A. 87.2 87.3 N.A. 65.9 69.9 65.8 51.3 N.A. N.A. N.A. N.A. 39
Protein Similarity: 100 99.4 99.4 95.1 N.A. 92.9 93 N.A. 80.2 83.6 80.1 71.1 N.A. N.A. N.A. N.A. 59.4
P-Site Identity: 100 100 100 53.3 N.A. 53.3 26.6 N.A. 33.3 0 13.3 6.6 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 66.6 N.A. 53.3 40 N.A. 53.3 13.3 20 6.6 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 34.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 0 0 0 0 0 0 0 9 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 0 0 0 9 0 17 0 0 0 9 9 0 0 50 9 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 0 9 9 0 % F
% Gly: 0 42 17 9 17 9 67 9 0 17 0 9 0 0 9 % G
% His: 0 0 0 0 0 0 0 9 34 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 0 9 0 50 9 0 17 9 % K
% Leu: 17 0 9 0 0 59 0 0 9 0 0 9 42 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 25 17 0 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 42 17 0 0 9 0 0 0 0 17 17 0 9 0 50 % P
% Gln: 0 17 0 9 9 0 0 0 9 0 0 9 0 0 0 % Q
% Arg: 0 17 9 0 9 0 0 25 34 0 0 9 0 9 0 % R
% Ser: 25 9 25 17 0 9 9 50 0 25 0 17 17 0 9 % S
% Thr: 0 0 9 9 34 0 25 9 0 25 9 0 17 0 9 % T
% Val: 9 0 9 0 0 0 0 0 0 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _