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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM32
All Species:
7.58
Human Site:
S759
Identified Species:
23.81
UniProt:
Q8TC27
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC27
NP_659441.3
787
87934
S759
S
S
S
Q
A
D
T
S
K
S
K
S
E
D
S
Chimpanzee
Pan troglodytes
XP_519720
629
70897
K602
V
L
A
R
K
Q
L
K
K
W
F
A
K
E
E
Rhesus Macaque
Macaca mulatta
XP_001095172
855
95089
S827
S
S
G
Q
A
D
T
S
K
S
K
S
E
D
S
Dog
Lupus familis
XP_532797
715
80116
L688
F
Y
I
A
L
P
V
L
I
I
V
T
I
I
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8K410
750
83594
S723
K
E
E
E
S
M
S
S
E
S
K
S
E
D
S
Rat
Rattus norvegicus
Q63202
737
82292
K710
V
L
I
G
M
L
V
K
V
Y
S
Q
R
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517253
692
76612
G665
C
V
D
V
S
V
L
G
F
D
C
Y
L
K
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001079073
873
95243
N774
G
P
P
R
N
A
L
N
V
P
P
N
R
G
T
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.5
83.2
61.5
N.A.
57
36.9
N.A.
38.1
N.A.
30.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
79.8
87.1
73.9
N.A.
70.3
56.4
N.A.
53.3
N.A.
48.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
93.3
0
N.A.
46.6
0
N.A.
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
93.3
13.3
N.A.
73.3
0
N.A.
6.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
13
25
13
0
0
0
0
0
13
0
0
13
% A
% Cys:
13
0
0
0
0
0
0
0
0
0
13
0
0
0
13
% C
% Asp:
0
0
13
0
0
25
0
0
0
13
0
0
0
38
0
% D
% Glu:
0
13
13
13
0
0
0
0
13
0
0
0
38
13
13
% E
% Phe:
13
0
0
0
0
0
0
0
13
0
13
0
0
0
0
% F
% Gly:
13
0
13
13
0
0
0
13
0
0
0
0
0
13
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
25
0
0
0
0
0
13
13
0
0
13
13
0
% I
% Lys:
13
0
0
0
13
0
0
25
38
0
38
0
13
25
13
% K
% Leu:
0
25
0
0
13
13
38
13
0
0
0
0
13
0
0
% L
% Met:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
13
0
0
13
0
0
0
13
0
0
0
% N
% Pro:
0
13
13
0
0
13
0
0
0
13
13
0
0
0
0
% P
% Gln:
0
0
0
25
0
13
0
0
0
0
0
13
0
0
0
% Q
% Arg:
0
0
0
25
0
0
0
0
0
0
0
0
25
0
0
% R
% Ser:
25
25
13
0
25
0
13
38
0
38
13
38
0
0
38
% S
% Thr:
0
0
0
0
0
0
25
0
0
0
0
13
0
0
13
% T
% Val:
25
13
0
13
0
13
25
0
25
0
13
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% W
% Tyr:
0
13
0
0
0
0
0
0
0
13
0
13
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _