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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CAGE1
All Species:
3.03
Human Site:
S249
Identified Species:
8.33
UniProt:
Q8TC20
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC20
NP_995586.1
777
90250
S249
E
I
P
E
M
S
V
S
Y
E
K
E
V
T
A
Chimpanzee
Pan troglodytes
XP_518225
827
95998
S249
Y
G
E
I
P
E
M
S
V
S
Y
E
K
E
V
Rhesus Macaque
Macaca mulatta
XP_001084947
771
89261
S249
Y
G
E
I
P
E
M
S
V
S
Y
A
K
E
V
Dog
Lupus familis
XP_851541
843
96232
K300
E
N
I
V
V
S
S
K
G
V
Q
S
F
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5IR70
849
97086
G251
S
K
E
V
Q
N
S
G
E
I
S
E
L
S
V
Rat
Rattus norvegicus
Q66HB6
847
97424
G257
E
F
S
D
M
S
V
G
P
Q
E
E
V
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510263
483
55537
P17
K
S
E
N
T
Y
P
P
E
K
L
D
I
C
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJE5
1690
189046
Q682
K
T
E
K
E
L
V
Q
S
K
E
Q
A
A
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786861
1624
188394
T389
L
E
E
K
S
A
K
T
E
D
R
L
T
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92
82.3
47.6
N.A.
43.5
42.7
N.A.
25.3
N.A.
N.A.
N.A.
N.A.
20.2
N.A.
N.A.
20
Protein Similarity:
100
92.9
87.7
63.1
N.A.
58.6
59.6
N.A.
40.1
N.A.
N.A.
N.A.
N.A.
31.7
N.A.
N.A.
33
P-Site Identity:
100
13.3
6.6
13.3
N.A.
6.6
46.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
20
13.3
26.6
N.A.
26.6
66.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
12
0
0
0
0
0
12
12
12
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
0
0
0
12
0
0
0
0
0
12
0
12
0
0
12
% D
% Glu:
34
12
67
12
12
23
0
0
34
12
23
45
0
45
12
% E
% Phe:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% F
% Gly:
0
23
0
0
0
0
0
23
12
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
12
12
23
0
0
0
0
0
12
0
0
12
0
0
% I
% Lys:
23
12
0
23
0
0
12
12
0
23
12
0
23
0
12
% K
% Leu:
12
0
0
0
0
12
0
0
0
0
12
12
12
0
12
% L
% Met:
0
0
0
0
23
0
23
0
0
0
0
0
0
0
0
% M
% Asn:
0
12
0
12
0
12
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
12
0
23
0
12
12
12
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
12
0
0
12
0
12
12
12
0
0
12
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% R
% Ser:
12
12
12
0
12
34
23
34
12
23
12
12
0
12
0
% S
% Thr:
0
12
0
0
12
0
0
12
0
0
0
0
12
23
0
% T
% Val:
0
0
0
23
12
0
34
0
23
12
0
0
23
0
34
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
23
0
0
0
0
12
0
0
12
0
23
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _