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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MDM1
All Species:
10
Human Site:
S407
Identified Species:
24.44
UniProt:
Q8TC05
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TC05
NP_064513.1
714
80735
S407
K
T
L
Q
K
C
P
S
T
E
P
E
E
K
G
Chimpanzee
Pan troglodytes
XP_509206
714
80684
S407
K
T
L
Q
K
C
P
S
T
E
P
E
E
K
G
Rhesus Macaque
Macaca mulatta
XP_001117173
720
81656
S408
K
T
L
Q
K
C
P
S
T
E
P
E
E
K
R
Dog
Lupus familis
XP_531669
782
87790
P476
K
T
L
Q
K
C
P
P
T
T
L
E
E
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D067
708
79671
P408
R
T
P
Q
K
H
P
P
T
K
L
E
E
R
K
Rat
Rattus norvegicus
Q5PQN4
719
80679
P417
R
T
L
Q
K
H
P
P
T
K
L
E
E
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511246
686
76752
K395
G
S
A
A
V
E
E
K
K
A
S
E
E
A
K
Chicken
Gallus gallus
Q5ZMW6
691
77332
T387
E
Q
S
H
Q
D
D
T
E
K
K
G
L
S
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5RHU7
656
74275
L383
H
I
I
E
A
L
D
L
A
R
A
G
S
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799039
812
89995
A469
G
A
R
P
S
A
S
A
P
D
L
G
H
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
94.4
73.7
N.A.
70.3
68.5
N.A.
50.4
44.5
N.A.
36.4
N.A.
N.A.
N.A.
N.A.
21.1
Protein Similarity:
100
99.3
96.3
81.1
N.A.
79.4
77.7
N.A.
64.4
60.3
N.A.
52.9
N.A.
N.A.
N.A.
N.A.
37.5
P-Site Identity:
100
100
93.3
73.3
N.A.
46.6
60
N.A.
13.3
0
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
93.3
73.3
N.A.
66.6
73.3
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
10
10
0
10
10
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
40
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
20
0
0
10
0
0
0
0
10
% D
% Glu:
10
0
0
10
0
10
10
0
10
30
0
70
70
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
20
0
0
0
0
0
0
0
0
0
0
30
0
0
20
% G
% His:
10
0
0
10
0
20
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
40
0
0
0
60
0
0
10
10
30
10
0
0
50
30
% K
% Leu:
0
0
50
0
0
10
0
10
0
0
40
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
10
10
0
0
60
30
10
0
30
0
0
0
10
% P
% Gln:
0
10
0
60
10
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
20
0
10
0
0
0
0
0
0
10
0
0
0
10
30
% R
% Ser:
0
10
10
0
10
0
10
30
0
0
10
0
10
10
0
% S
% Thr:
0
60
0
0
0
0
0
10
60
10
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _