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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR66 All Species: 4.55
Human Site: S486 Identified Species: 14.29
UniProt: Q8TBY9 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBY9 NP_653269.3 1154 130645 S486 D I H R P P S S A S T F L G F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_534664 1163 132490 S487 D I H R P S S S A S T S V G F
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus XP_001079344 1256 140835 A469 A D A D S A S A D S A V S E F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506270 1113 125384 Q460 I K A I K L I Q L Q T D G I T
Chicken Gallus gallus XP_415147 988 109326 H335 K E P Q G R L H G M K A T K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_697723 906 101629 H253 F Y N W E R G H L E Y S A P E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397134 662 76259 L9 V D K I P S T L T V N L E I L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785437 1181 130214 S463 R P T S G P P S L E P S P N K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 79.7 N.A. N.A. 63.9 N.A. 59.6 45.9 N.A. 38.2 N.A. N.A. 22.3 N.A. 41.1
Protein Similarity: 100 N.A. N.A. 87.7 N.A. N.A. 75.8 N.A. 74 61.2 N.A. 54.5 N.A. N.A. 35.5 N.A. 59.7
P-Site Identity: 100 N.A. N.A. 80 N.A. N.A. 20 N.A. 6.6 0 N.A. 0 N.A. N.A. 6.6 N.A. 13.3
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. N.A. 26.6 N.A. 6.6 6.6 N.A. 6.6 N.A. N.A. 13.3 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 25 0 0 13 0 13 25 0 13 13 13 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 25 25 0 13 0 0 0 0 13 0 0 13 0 0 0 % D
% Glu: 0 13 0 0 13 0 0 0 0 25 0 0 13 13 13 % E
% Phe: 13 0 0 0 0 0 0 0 0 0 0 13 0 0 38 % F
% Gly: 0 0 0 0 25 0 13 0 13 0 0 0 13 25 0 % G
% His: 0 0 25 0 0 0 0 25 0 0 0 0 0 0 0 % H
% Ile: 13 25 0 25 0 0 13 0 0 0 0 0 0 25 0 % I
% Lys: 13 13 13 0 13 0 0 0 0 0 13 0 0 13 13 % K
% Leu: 0 0 0 0 0 13 13 13 38 0 0 13 13 0 25 % L
% Met: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 0 0 13 0 0 13 0 % N
% Pro: 0 13 13 0 38 25 13 0 0 0 13 0 13 13 0 % P
% Gln: 0 0 0 13 0 0 0 13 0 13 0 0 0 0 0 % Q
% Arg: 13 0 0 25 0 25 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 13 13 25 38 38 0 38 0 38 13 0 0 % S
% Thr: 0 0 13 0 0 0 13 0 13 0 38 0 13 0 13 % T
% Val: 13 0 0 0 0 0 0 0 0 13 0 13 13 0 0 % V
% Trp: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 13 0 0 0 0 0 0 0 0 13 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _