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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NANP All Species: 21.52
Human Site: Y225 Identified Species: 43.03
UniProt: Q8TBE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBE9 NP_689880.1 248 27813 Y225 K S S P V P H Y M V S S V L E
Chimpanzee Pan troglodytes XP_001150653 141 15333 M119 S S P V P H Y M V S S V L E L
Rhesus Macaque Macaca mulatta XP_001101196 248 27842 Y225 K S S P V P H Y I V S S V L E
Dog Lupus familis XP_850213 248 27832 Y225 K S S P M P H Y I V S S V L E
Cat Felis silvestris
Mouse Mus musculus Q9CPT3 248 27790 Y225 T S S P M P H Y M V S S V L E
Rat Rattus norvegicus Q5M969 248 27722 Y225 T S S P M P H Y M V S S V L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519927 322 35539 Y290 N P S P I P H Y I V S S V L E
Chicken Gallus gallus Q5F4B1 312 32977 D287 V R G H Q E S D C P A R Q G L
Frog Xenopus laevis NP_001084546 240 26870 V218 Q N P S I N K V M P T P H Y T
Zebra Danio Brachydanio rerio NP_001018593 242 26737 D220 G S K S L P Q D S V T P D Y T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572257 355 40350 E241 A Q S L E D V E Y K P H V K L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787883 237 26867 K215 Q P S S D Y V K A D Y T I K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.4 98.7 91.1 N.A. 93.9 94.3 N.A. 57.7 20.5 57.2 48.7 N.A. 22.8 N.A. N.A. 39.1
Protein Similarity: 100 56.4 99.1 96.3 N.A. 97.9 97.9 N.A. 65.5 32.3 73.3 64.9 N.A. 36.9 N.A. N.A. 54
P-Site Identity: 100 13.3 93.3 86.6 N.A. 86.6 86.6 N.A. 73.3 0 6.6 20 N.A. 13.3 N.A. N.A. 6.6
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 93.3 N.A. 86.6 6.6 33.3 33.3 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 0 0 0 0 9 0 9 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 9 0 17 0 9 0 0 9 0 0 % D
% Glu: 0 0 0 0 9 9 0 9 0 0 0 0 0 9 50 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % G
% His: 0 0 0 9 0 9 50 0 0 0 0 9 9 0 0 % H
% Ile: 0 0 0 0 17 0 0 0 25 0 0 0 9 0 0 % I
% Lys: 25 0 9 0 0 0 9 9 0 9 0 0 0 17 0 % K
% Leu: 0 0 0 9 9 0 0 0 0 0 0 0 9 50 25 % L
% Met: 0 0 0 0 25 0 0 9 34 0 0 0 0 0 0 % M
% Asn: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 17 50 9 59 0 0 0 17 9 17 0 0 0 % P
% Gln: 17 9 0 0 9 0 9 0 0 0 0 0 9 0 0 % Q
% Arg: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % R
% Ser: 9 59 67 25 0 0 9 0 9 9 59 50 0 0 9 % S
% Thr: 17 0 0 0 0 0 0 0 0 0 17 9 0 0 17 % T
% Val: 9 0 0 9 17 0 17 9 9 59 0 9 59 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 9 50 9 0 9 0 0 17 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _