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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NANP All Species: 19.39
Human Site: S219 Identified Species: 38.79
UniProt: Q8TBE9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TBE9 NP_689880.1 248 27813 S219 N G I V P L K S S P V P H Y M
Chimpanzee Pan troglodytes XP_001150653 141 15333 S113 G I V P L K S S P V P H Y M V
Rhesus Macaque Macaca mulatta XP_001101196 248 27842 S219 N G I V P L K S S P V P H Y I
Dog Lupus familis XP_850213 248 27832 S219 N G I M P L K S S P M P H Y I
Cat Felis silvestris
Mouse Mus musculus Q9CPT3 248 27790 S219 S G R V P L T S S P M P H Y M
Rat Rattus norvegicus Q5M969 248 27722 S219 S G G V P L T S S P M P H Y M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519927 322 35539 P284 T G T P P S N P S P I P H Y I
Chicken Gallus gallus Q5F4B1 312 32977 R281 V S T L E E V R G H Q E S D C
Frog Xenopus laevis NP_001084546 240 26870 N212 A T I W I N Q N P S I N K V M
Zebra Danio Brachydanio rerio NP_001018593 242 26737 S214 T V W I N A G S K S L P Q D S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572257 355 40350 Q235 S N S S A A A Q S L E D V E Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787883 237 26867 P209 I N P H G K Q P S S D Y V K A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.4 98.7 91.1 N.A. 93.9 94.3 N.A. 57.7 20.5 57.2 48.7 N.A. 22.8 N.A. N.A. 39.1
Protein Similarity: 100 56.4 99.1 96.3 N.A. 97.9 97.9 N.A. 65.5 32.3 73.3 64.9 N.A. 36.9 N.A. N.A. 54
P-Site Identity: 100 6.6 93.3 80 N.A. 73.3 73.3 N.A. 46.6 0 13.3 13.3 N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 26.6 100 100 N.A. 86.6 86.6 N.A. 60 6.6 33.3 26.6 N.A. 13.3 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 0 0 9 17 9 0 0 0 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 9 9 0 17 0 % D
% Glu: 0 0 0 0 9 9 0 0 0 0 9 9 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 50 9 0 9 0 9 0 9 0 0 0 0 0 0 % G
% His: 0 0 0 9 0 0 0 0 0 9 0 9 50 0 0 % H
% Ile: 9 9 34 9 9 0 0 0 0 0 17 0 0 0 25 % I
% Lys: 0 0 0 0 0 17 25 0 9 0 0 0 9 9 0 % K
% Leu: 0 0 0 9 9 42 0 0 0 9 9 0 0 0 0 % L
% Met: 0 0 0 9 0 0 0 0 0 0 25 0 0 9 34 % M
% Asn: 25 17 0 0 9 9 9 9 0 0 0 9 0 0 0 % N
% Pro: 0 0 9 17 50 0 0 17 17 50 9 59 0 0 0 % P
% Gln: 0 0 0 0 0 0 17 9 0 0 9 0 9 0 0 % Q
% Arg: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 25 9 9 9 0 9 9 59 67 25 0 0 9 0 9 % S
% Thr: 17 9 17 0 0 0 17 0 0 0 0 0 0 0 0 % T
% Val: 9 9 9 34 0 0 9 0 0 9 17 0 17 9 9 % V
% Trp: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 9 9 50 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _