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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A14
All Species:
20.61
Human Site:
Y731
Identified Species:
37.78
UniProt:
Q8TBB6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBB6
NP_066000.2
771
84080
Y731
T
E
D
K
G
F
Y
Y
Q
Q
M
S
D
A
K
Chimpanzee
Pan troglodytes
XP_526378
771
84015
Y731
T
E
D
K
G
F
Y
Y
Q
Q
M
S
D
A
K
Rhesus Macaque
Macaca mulatta
XP_001088713
771
83893
Y731
A
E
D
K
G
F
Y
Y
Q
Q
M
S
D
A
K
Dog
Lupus familis
XP_545285
771
83977
Y731
A
E
D
K
G
F
Y
Y
Q
Q
M
S
D
A
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXR1
771
83965
Y731
A
E
D
K
G
F
Y
Y
Q
Q
M
S
D
A
K
Rat
Rattus norvegicus
P30823
624
67249
A585
Q
G
T
W
V
R
F
A
V
W
M
L
I
A
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521594
562
60779
L523
Q
P
E
N
P
K
K
L
P
Y
M
A
P
C
L
Chicken
Gallus gallus
B3TP03
654
71198
G615
G
R
H
S
D
G
D
G
D
S
C
S
E
N
S
Frog
Xenopus laevis
Q6DCE8
622
66913
S583
F
G
Y
G
I
R
H
S
I
E
R
L
H
L
K
Zebra Danio
Brachydanio rerio
Q5PR34
640
69447
H601
Y
F
G
Y
G
M
W
H
S
D
E
R
K
R
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608350
812
87487
Y733
S
T
E
Q
R
Y
N
Y
G
K
T
T
S
S
S
Honey Bee
Apis mellifera
XP_393071
791
86543
A752
Y
E
S
Q
Q
L
D
A
F
G
Q
P
V
F
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780655
824
91437
G784
E
W
A
Q
S
P
R
G
D
G
I
I
M
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
97
N.A.
96.7
38.2
N.A.
66
37.4
39.2
38.3
N.A.
41.7
42.5
N.A.
46
Protein Similarity:
100
99.7
99.3
98.3
N.A.
98.3
54.9
N.A.
70
55.7
56
54.9
N.A.
57.7
60.6
N.A.
59.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
13.3
N.A.
6.6
6.6
6.6
6.6
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
93.3
93.3
N.A.
93.3
20
N.A.
20
13.3
20
20
N.A.
53.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
0
0
0
16
0
0
0
8
0
47
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
0
39
0
8
0
16
0
16
8
0
0
39
0
0
% D
% Glu:
8
47
16
0
0
0
0
0
0
8
8
0
8
0
0
% E
% Phe:
8
8
0
0
0
39
8
0
8
0
0
0
0
8
8
% F
% Gly:
8
16
8
8
47
8
0
16
8
16
0
0
0
0
8
% G
% His:
0
0
8
0
0
0
8
8
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
8
0
0
0
8
0
8
8
8
0
0
% I
% Lys:
0
0
0
39
0
8
8
0
0
8
0
0
8
0
47
% K
% Leu:
0
0
0
0
0
8
0
8
0
0
0
16
0
8
8
% L
% Met:
0
0
0
0
0
8
0
0
0
0
54
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
8
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
8
8
0
0
8
0
0
8
8
0
0
% P
% Gln:
16
0
0
24
8
0
0
0
39
39
8
0
0
0
0
% Q
% Arg:
0
8
0
0
8
16
8
0
0
0
8
8
0
8
0
% R
% Ser:
8
0
8
8
8
0
0
8
8
8
0
47
8
16
16
% S
% Thr:
16
8
8
0
0
0
0
0
0
0
8
8
0
0
8
% T
% Val:
0
0
0
0
8
0
0
0
8
0
0
0
8
0
0
% V
% Trp:
0
8
0
8
0
0
8
0
0
8
0
0
0
0
0
% W
% Tyr:
16
0
8
8
0
8
39
47
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _