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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A14
All Species:
18.48
Human Site:
Y541
Identified Species:
33.89
UniProt:
Q8TBB6
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBB6
NP_066000.2
771
84080
Y541
K
K
L
I
G
P
H
Y
Y
T
M
R
I
R
L
Chimpanzee
Pan troglodytes
XP_526378
771
84015
Y541
K
K
L
I
G
P
H
Y
Y
T
M
R
I
R
L
Rhesus Macaque
Macaca mulatta
XP_001088713
771
83893
Y541
K
K
L
I
G
P
H
Y
Y
T
L
R
I
R
L
Dog
Lupus familis
XP_545285
771
83977
Y541
K
K
L
I
G
P
R
Y
Y
T
M
R
I
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXR1
771
83965
Y541
K
K
L
I
G
P
R
Y
Y
T
M
R
I
R
L
Rat
Rattus norvegicus
P30823
624
67249
L400
V
M
A
F
L
F
E
L
K
D
L
V
D
L
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521594
562
60779
G337
Q
P
E
S
D
I
D
G
F
V
K
F
L
S
E
Chicken
Gallus gallus
B3TP03
654
71198
I430
L
V
A
T
C
V
L
I
L
R
Y
Q
P
S
L
Frog
Xenopus laevis
Q6DCE8
622
66913
A398
T
I
V
S
G
V
V
A
A
L
M
A
F
L
F
Zebra Danio
Brachydanio rerio
Q5PR34
640
69447
T416
V
D
M
M
S
I
G
T
L
L
A
Y
S
L
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608350
812
87487
H546
N
F
V
T
R
K
I
H
D
Y
A
Y
L
C
P
Honey Bee
Apis mellifera
XP_393071
791
86543
R563
P
P
L
N
Y
L
Q
R
R
L
Q
A
A
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780655
824
91437
E595
T
Q
G
S
T
L
Q
E
A
G
P
E
Q
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
97
N.A.
96.7
38.2
N.A.
66
37.4
39.2
38.3
N.A.
41.7
42.5
N.A.
46
Protein Similarity:
100
99.7
99.3
98.3
N.A.
98.3
54.9
N.A.
70
55.7
56
54.9
N.A.
57.7
60.6
N.A.
59.8
P-Site Identity:
100
100
93.3
93.3
N.A.
93.3
0
N.A.
0
6.6
13.3
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
20
13.3
20
20
N.A.
20
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
8
16
0
16
16
8
0
0
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
8
0
8
0
8
8
0
0
8
0
0
% D
% Glu:
0
0
8
0
0
0
8
8
0
0
0
8
0
0
8
% E
% Phe:
0
8
0
8
0
8
0
0
8
0
0
8
8
0
8
% F
% Gly:
0
0
8
0
47
0
8
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
24
8
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
39
0
16
8
8
0
0
0
0
39
0
0
% I
% Lys:
39
39
0
0
0
8
0
0
8
0
8
0
0
0
0
% K
% Leu:
8
0
47
0
8
16
8
8
16
24
16
0
16
31
54
% L
% Met:
0
8
8
8
0
0
0
0
0
0
39
0
0
0
8
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
16
0
0
0
39
0
0
0
0
8
0
8
0
8
% P
% Gln:
8
8
0
0
0
0
16
0
0
0
8
8
8
8
0
% Q
% Arg:
0
0
0
0
8
0
16
8
8
8
0
39
0
39
0
% R
% Ser:
0
0
0
24
8
0
0
0
0
0
0
0
8
16
0
% S
% Thr:
16
0
0
16
8
0
0
8
0
39
0
0
0
0
0
% T
% Val:
16
8
16
0
0
16
8
0
0
8
0
8
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
39
39
8
8
16
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _