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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC7A14
All Species:
19.09
Human Site:
S445
Identified Species:
35
UniProt:
Q8TBB6
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBB6
NP_066000.2
771
84080
S445
D
G
F
V
K
F
L
S
E
E
H
T
K
K
K
Chimpanzee
Pan troglodytes
XP_526378
771
84015
S445
D
G
F
V
K
F
L
S
E
E
H
T
K
K
K
Rhesus Macaque
Macaca mulatta
XP_001088713
771
83893
S445
D
G
F
V
K
F
L
S
E
E
H
T
K
K
K
Dog
Lupus familis
XP_545285
771
83977
S445
D
G
F
V
K
F
L
S
Q
E
H
T
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BXR1
771
83965
S445
D
G
F
V
K
F
L
S
E
E
H
T
K
K
K
Rat
Rattus norvegicus
P30823
624
67249
L305
G
V
S
A
A
L
T
L
M
M
P
Y
F
C
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521594
562
60779
A242
V
V
A
I
G
S
V
A
G
L
I
V
S
L
L
Chicken
Gallus gallus
B3TP03
654
71198
G335
A
F
A
Y
V
G
W
G
P
A
K
Y
V
V
A
Frog
Xenopus laevis
Q6DCE8
622
66913
A303
S
L
S
I
C
F
F
A
Y
F
G
V
S
A
S
Zebra Danio
Brachydanio rerio
Q5PR34
640
69447
K321
P
Y
Y
L
L
D
E
K
S
P
L
P
L
A
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608350
812
87487
Q444
L
V
E
L
L
P
A
Q
L
R
T
P
V
A
H
Honey Bee
Apis mellifera
XP_393071
791
86543
S468
L
V
E
L
L
P
Q
S
L
R
T
P
C
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780655
824
91437
N491
F
R
F
L
G
N
I
N
V
V
T
N
T
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
97
N.A.
96.7
38.2
N.A.
66
37.4
39.2
38.3
N.A.
41.7
42.5
N.A.
46
Protein Similarity:
100
99.7
99.3
98.3
N.A.
98.3
54.9
N.A.
70
55.7
56
54.9
N.A.
57.7
60.6
N.A.
59.8
P-Site Identity:
100
100
100
93.3
N.A.
100
0
N.A.
0
0
6.6
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
0
N.A.
20
0
20
13.3
N.A.
6.6
20
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
8
0
8
16
0
8
0
0
0
24
16
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% C
% Asp:
39
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
16
0
0
0
8
0
31
39
0
0
0
0
0
% E
% Phe:
8
8
47
0
0
47
8
0
0
8
0
0
8
0
8
% F
% Gly:
8
39
0
0
16
8
0
8
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
39
0
0
0
8
% H
% Ile:
0
0
0
16
0
0
8
0
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
39
0
0
8
0
0
8
0
39
39
39
% K
% Leu:
16
8
0
31
24
8
39
8
16
8
8
0
8
8
16
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% N
% Pro:
8
0
0
0
0
16
0
0
8
8
8
24
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
8
8
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
16
0
0
0
8
0
% R
% Ser:
8
0
16
0
0
8
0
47
8
0
0
0
16
0
16
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
24
39
8
0
0
% T
% Val:
8
31
0
39
8
0
8
0
8
8
0
16
16
8
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
8
8
0
0
0
0
8
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _