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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHDC4
All Species:
26.06
Human Site:
S461
Identified Species:
47.78
UniProt:
Q8TBB5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TBB5
NP_060036.2
520
57892
S461
G
D
R
Q
V
T
L
S
D
L
H
C
L
D
L
Chimpanzee
Pan troglodytes
XP_001157133
541
60088
S461
G
D
R
Q
V
T
L
S
D
L
H
C
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001086874
522
58135
S461
G
D
R
Q
V
T
L
S
D
L
H
C
L
D
L
Dog
Lupus familis
XP_546788
667
72888
S570
G
D
R
Q
I
T
L
S
D
L
Y
C
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q921I2
584
64842
S461
G
D
R
Q
V
T
L
S
D
L
Y
C
L
D
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508869
624
70162
N508
G
D
R
Q
F
T
L
N
D
F
Y
C
I
D
L
Chicken
Gallus gallus
NP_001025749
579
65046
S462
G
D
R
Q
F
T
L
S
D
L
Y
S
I
D
L
Frog
Xenopus laevis
NP_001079516
578
65206
N463
G
D
R
Q
F
T
L
N
D
L
Y
S
L
D
L
Zebra Danio
Brachydanio rerio
NP_001119902
585
65979
S466
G
D
R
Q
F
T
L
S
D
L
Y
S
L
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648590
509
56333
N455
D
D
K
Q
L
T
Y
N
D
F
Y
A
L
D
L
Honey Bee
Apis mellifera
XP_624296
469
54330
F419
L
Y
L
Y
G
G
M
F
E
D
G
N
R
Q
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SDM9
470
51651
F420
Q
W
E
R
L
D
K
F
G
G
E
E
E
T
P
Baker's Yeast
Sacchar. cerevisiae
Q08979
651
75415
N483
G
E
K
D
Y
P
I
N
S
F
Y
S
I
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
95.7
63.2
N.A.
72.7
N.A.
N.A.
62.1
69
64.3
63.4
N.A.
41.1
41.5
N.A.
N.A.
Protein Similarity:
100
94.6
97.5
70.9
N.A.
79.4
N.A.
N.A.
72.4
79.2
76.1
74
N.A.
59.6
58.4
N.A.
N.A.
P-Site Identity:
100
100
100
86.6
N.A.
93.3
N.A.
N.A.
66.6
73.3
73.3
80
N.A.
46.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
86.6
86.6
86.6
86.6
N.A.
73.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
27.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.7
41.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
47
0
0
0
% C
% Asp:
8
77
0
8
0
8
0
0
77
8
0
0
0
85
0
% D
% Glu:
0
8
8
0
0
0
0
0
8
0
8
8
8
0
0
% E
% Phe:
0
0
0
0
31
0
0
16
0
24
0
0
0
0
0
% F
% Gly:
77
0
0
0
8
8
0
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
24
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
8
0
0
0
0
0
24
0
0
% I
% Lys:
0
0
16
0
0
0
8
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
8
0
16
0
70
0
0
62
0
0
62
0
85
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
31
0
0
0
8
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
0
77
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
70
8
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
0
54
8
0
0
31
0
0
0
% S
% Thr:
0
0
0
0
0
77
0
0
0
0
0
0
0
8
0
% T
% Val:
0
0
0
0
31
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
8
0
8
0
0
0
62
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _