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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGCLL1
All Species:
13.33
Human Site:
Y243
Identified Species:
24.44
UniProt:
Q8TB92
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB92
NP_001035865.1
370
39514
Y243
R
L
Y
G
M
G
C
Y
E
I
S
L
G
D
T
Chimpanzee
Pan troglodytes
XP_001166273
325
34328
L202
M
G
C
Y
E
I
S
L
G
D
T
I
G
V
G
Rhesus Macaque
Macaca mulatta
XP_001105003
444
47056
Y317
R
L
Y
S
M
G
C
Y
E
I
S
L
G
D
T
Dog
Lupus familis
XP_538973
343
36798
T220
Y
E
I
S
L
G
D
T
T
G
V
G
T
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZS7
343
36632
T220
Y
E
I
S
L
G
D
T
I
G
V
G
T
P
G
Rat
Rattus norvegicus
P97519
325
34173
L202
M
G
C
Y
E
I
S
L
G
D
T
I
G
V
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P35915
298
31418
L175
M
G
C
Y
E
I
S
L
G
D
R
I
G
I
G
Frog
Xenopus laevis
NP_001085152
328
34788
L205
M
G
C
Y
E
I
S
L
G
D
T
I
G
V
G
Zebra Danio
Brachydanio rerio
A8WG57
335
35873
L212
L
G
C
Y
E
V
S
L
G
D
T
I
G
V
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196745
313
33056
L190
M
G
C
Y
E
I
S
L
G
D
T
I
G
V
G
Poplar Tree
Populus trichocarpa
XP_002308880
293
30640
Y170
K
L
C
D
M
G
C
Y
E
I
S
L
G
D
T
Maize
Zea mays
NP_001132253
434
44858
Y300
E
L
Y
D
M
G
C
Y
E
V
S
L
G
D
T
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81027
468
50558
F333
E
L
Y
D
M
G
C
F
E
I
S
L
G
D
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.6
80.6
88.6
N.A.
85.1
61.3
N.A.
N.A.
58.6
58.1
64.5
N.A.
N.A.
N.A.
N.A.
55.4
Protein Similarity:
100
74
81
90.2
N.A.
88.6
74.8
N.A.
N.A.
69.4
70.5
78.3
N.A.
N.A.
N.A.
N.A.
68.6
P-Site Identity:
100
6.6
93.3
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
93.3
13.3
N.A.
13.3
20
N.A.
N.A.
13.3
20
20
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
50.8
47.9
N.A.
45.7
N.A.
N.A.
Protein Similarity:
63.5
61.5
N.A.
59.6
N.A.
N.A.
P-Site Identity:
80
80
N.A.
80
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
54
0
0
0
39
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
24
0
0
16
0
0
47
0
0
0
39
0
% D
% Glu:
16
16
0
0
47
0
0
0
39
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
47
0
8
0
54
0
0
47
16
0
16
85
0
62
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
39
0
0
8
31
0
47
0
8
0
% I
% Lys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
39
0
0
16
0
0
47
0
0
0
39
0
0
0
% L
% Met:
39
0
0
0
39
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
16
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
24
0
0
47
0
0
0
39
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
8
0
39
0
16
0
39
% T
% Val:
0
0
0
0
0
8
0
0
0
8
16
0
0
39
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
31
47
0
0
0
31
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _