KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGCLL1
All Species:
16.36
Human Site:
T255
Identified Species:
30
UniProt:
Q8TB92
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB92
NP_001035865.1
370
39514
T255
G
D
T
I
G
V
G
T
P
G
S
M
K
R
M
Chimpanzee
Pan troglodytes
XP_001166273
325
34328
M214
G
V
G
T
P
G
I
M
K
D
M
L
S
A
V
Rhesus Macaque
Macaca mulatta
XP_001105003
444
47056
T329
G
D
T
I
G
V
G
T
P
G
S
M
K
R
M
Dog
Lupus familis
XP_538973
343
36798
M232
T
P
G
S
M
K
R
M
L
E
S
V
M
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZS7
343
36632
M232
T
P
G
S
M
K
M
M
L
E
S
V
M
K
E
Rat
Rattus norvegicus
P97519
325
34173
M214
G
V
G
T
P
G
L
M
K
D
M
L
T
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P35915
298
31418
M187
G
I
G
T
P
G
S
M
K
E
M
L
A
A
V
Frog
Xenopus laevis
NP_001085152
328
34788
M217
G
V
G
T
P
G
G
M
R
D
M
L
S
A
V
Zebra Danio
Brachydanio rerio
A8WG57
335
35873
M224
G
V
G
T
A
G
S
M
A
E
M
L
S
D
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196745
313
33056
M202
G
V
G
T
P
G
Q
M
Q
V
L
L
E
T
V
Poplar Tree
Populus trichocarpa
XP_002308880
293
30640
T182
G
D
T
I
G
V
G
T
P
G
T
V
I
P
M
Maize
Zea mays
NP_001132253
434
44858
T312
G
D
T
I
G
V
G
T
P
G
T
V
V
P
M
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81027
468
50558
T345
G
D
T
I
G
I
G
T
P
G
S
V
V
P
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.6
80.6
88.6
N.A.
85.1
61.3
N.A.
N.A.
58.6
58.1
64.5
N.A.
N.A.
N.A.
N.A.
55.4
Protein Similarity:
100
74
81
90.2
N.A.
88.6
74.8
N.A.
N.A.
69.4
70.5
78.3
N.A.
N.A.
N.A.
N.A.
68.6
P-Site Identity:
100
6.6
100
6.6
N.A.
6.6
6.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
20
N.A.
20
20
N.A.
N.A.
20
26.6
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
50.8
47.9
N.A.
45.7
N.A.
N.A.
Protein Similarity:
63.5
61.5
N.A.
59.6
N.A.
N.A.
P-Site Identity:
73.3
73.3
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
86.6
86.6
N.A.
86.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
0
0
8
0
0
0
8
31
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
39
0
0
0
0
0
0
0
24
0
0
0
8
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
31
0
0
8
0
16
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
85
0
62
0
39
47
47
0
0
39
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
39
0
8
8
0
0
0
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
16
0
0
24
0
0
0
16
16
0
% K
% Leu:
0
0
0
0
0
0
8
0
16
0
8
47
0
0
0
% L
% Met:
0
0
0
0
16
0
8
62
0
0
39
16
16
0
39
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
16
0
0
39
0
0
0
39
0
0
0
0
24
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
0
8
0
0
0
0
16
0
% R
% Ser:
0
0
0
16
0
0
16
0
0
0
39
0
24
0
0
% S
% Thr:
16
0
39
47
0
0
0
39
0
0
16
0
8
8
0
% T
% Val:
0
39
0
0
0
31
0
0
0
8
0
39
16
0
47
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _