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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMGCLL1
All Species:
7.27
Human Site:
T226
Identified Species:
13.33
UniProt:
Q8TB92
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB92
NP_001035865.1
370
39514
T226
C
P
Y
E
G
S
I
T
P
Q
K
V
T
E
V
Chimpanzee
Pan troglodytes
XP_001166273
325
34328
V185
G
K
I
S
P
A
K
V
A
E
V
T
K
K
F
Rhesus Macaque
Macaca mulatta
XP_001105003
444
47056
T300
C
P
Y
E
G
I
I
T
P
Q
K
V
T
E
V
Dog
Lupus familis
XP_538973
343
36798
V203
T
P
Q
K
V
T
E
V
S
K
K
L
Y
G
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8JZS7
343
36632
V203
T
P
Q
K
V
T
E
V
S
K
R
L
Y
G
M
Rat
Rattus norvegicus
P97519
325
34173
V185
G
K
V
S
P
A
K
V
A
E
V
A
K
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P35915
298
31418
V158
G
N
I
S
A
A
K
V
A
E
V
S
K
K
M
Frog
Xenopus laevis
NP_001085152
328
34788
V188
G
K
V
A
P
S
K
V
A
E
V
A
Y
K
M
Zebra Danio
Brachydanio rerio
A8WG57
335
35873
V195
G
Q
V
K
P
S
Q
V
T
K
V
A
K
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196745
313
33056
V173
G
A
V
Q
P
E
A
V
A
K
V
A
N
K
M
Poplar Tree
Populus trichocarpa
XP_002308880
293
30640
S153
C
P
V
E
G
M
V
S
P
S
K
V
A
Y
V
Maize
Zea mays
NP_001132253
434
44858
P283
C
P
V
D
G
P
V
P
P
S
N
V
A
Y
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O81027
468
50558
L316
C
P
V
E
G
P
V
L
P
S
K
V
A
Y
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
61.6
80.6
88.6
N.A.
85.1
61.3
N.A.
N.A.
58.6
58.1
64.5
N.A.
N.A.
N.A.
N.A.
55.4
Protein Similarity:
100
74
81
90.2
N.A.
88.6
74.8
N.A.
N.A.
69.4
70.5
78.3
N.A.
N.A.
N.A.
N.A.
68.6
P-Site Identity:
100
0
93.3
13.3
N.A.
6.6
0
N.A.
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
20
93.3
46.6
N.A.
46.6
26.6
N.A.
N.A.
26.6
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
50.8
47.9
N.A.
45.7
N.A.
N.A.
Protein Similarity:
63.5
61.5
N.A.
59.6
N.A.
N.A.
P-Site Identity:
53.3
40
N.A.
53.3
N.A.
N.A.
P-Site Similarity:
66.6
53.3
N.A.
60
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
24
8
0
39
0
0
31
24
0
0
% A
% Cys:
39
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
31
0
8
16
0
0
31
0
0
0
16
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% F
% Gly:
47
0
0
0
39
0
0
0
0
0
0
0
0
16
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
0
8
16
0
0
0
0
0
0
0
0
% I
% Lys:
0
24
0
24
0
0
31
0
0
31
39
0
31
39
0
% K
% Leu:
0
0
0
0
0
0
0
8
0
0
0
16
0
0
16
% L
% Met:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
39
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
8
0
8
0
0
% N
% Pro:
0
54
0
0
39
16
0
8
39
0
0
0
0
0
0
% P
% Gln:
0
8
16
8
0
0
8
0
0
16
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
0
0
24
0
24
0
8
16
24
0
8
0
0
0
% S
% Thr:
16
0
0
0
0
16
0
16
8
0
0
8
16
0
0
% T
% Val:
0
0
54
0
16
0
24
62
0
0
47
39
0
0
39
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
16
0
0
0
0
0
0
0
0
0
24
24
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _