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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC6
All Species:
30
Human Site:
Y140
Identified Species:
66
UniProt:
Q8TB45
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB45
NP_073620.2
409
46294
Y140
F
M
R
G
Q
R
L
Y
E
K
L
M
S
P
E
Chimpanzee
Pan troglodytes
XP_519926
207
22794
Rhesus Macaque
Macaca mulatta
XP_001097652
409
46319
Y140
F
M
R
G
Q
R
L
Y
E
K
L
M
S
P
E
Dog
Lupus familis
XP_539149
408
46002
Y139
F
M
R
G
Q
R
L
Y
E
K
L
M
S
P
E
Cat
Felis silvestris
Mouse
Mus musculus
Q570Y9
409
46101
Y140
F
M
R
G
Q
R
L
Y
E
K
L
M
S
P
E
Rat
Rattus norvegicus
XP_001066889
409
46208
Y140
F
M
R
G
Q
R
L
Y
E
K
L
M
S
P
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506508
409
46681
Y141
F
M
R
G
Q
S
L
Y
E
T
L
I
S
V
D
Chicken
Gallus gallus
XP_418463
397
45473
Y128
F
M
R
G
Q
R
L
Y
E
K
L
M
S
S
E
Frog
Xenopus laevis
NP_001088972
406
45836
Y128
C
V
R
G
H
R
L
Y
E
M
I
T
S
Q
E
Zebra Danio
Brachydanio rerio
NP_001070788
348
39828
F95
E
F
K
D
M
K
L
F
F
R
F
R
K
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189237
370
41450
T107
F
H
R
V
T
S
E
T
S
S
S
P
L
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.6
99.5
98.5
N.A.
96
97.8
N.A.
63.8
86.3
53
67.9
N.A.
N.A.
N.A.
N.A.
32.5
Protein Similarity:
100
50.6
99.5
98.5
N.A.
97.5
98.2
N.A.
78.4
90.2
67.2
75
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
66.6
93.3
53.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
0
100
100
N.A.
100
100
N.A.
80
93.3
66.6
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
0
0
0
10
19
% D
% Glu:
10
0
0
0
0
0
10
0
73
0
0
0
0
0
64
% E
% Phe:
73
10
0
0
0
0
0
10
10
0
10
0
0
0
0
% F
% Gly:
0
0
0
73
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
0
0
55
0
0
10
0
10
% K
% Leu:
0
0
0
0
0
0
82
0
0
0
64
0
10
10
0
% L
% Met:
0
64
0
0
10
0
0
0
0
10
0
55
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
46
0
% P
% Gln:
0
0
0
0
64
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
0
0
82
0
0
64
0
0
0
10
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
19
0
0
10
10
10
0
73
10
0
% S
% Thr:
0
0
0
0
10
0
0
10
0
10
0
10
0
0
0
% T
% Val:
0
10
0
10
0
0
0
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
73
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _