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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC6
All Species:
27.27
Human Site:
S389
Identified Species:
60
UniProt:
Q8TB45
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8TB45
NP_073620.2
409
46294
S389
H
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Chimpanzee
Pan troglodytes
XP_519926
207
22794
L191
R
T
V
S
N
L
I
L
T
G
P
R
T
I
V
Rhesus Macaque
Macaca mulatta
XP_001097652
409
46319
S389
H
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Dog
Lupus familis
XP_539149
408
46002
S388
H
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q570Y9
409
46101
S389
N
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Rat
Rattus norvegicus
XP_001066889
409
46208
S389
N
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506508
409
46681
S390
H
L
D
Y
Q
T
I
S
N
L
I
M
T
G
P
Chicken
Gallus gallus
XP_418463
397
45473
S377
H
V
D
Y
R
T
V
S
N
L
I
L
T
G
P
Frog
Xenopus laevis
NP_001088972
406
45836
N374
R
Y
D
C
Q
T
I
N
R
L
I
V
A
G
P
Zebra Danio
Brachydanio rerio
NP_001070788
348
39828
H332
V
R
G
S
K
P
C
H
I
Q
A
V
D
P
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189237
370
41450
G346
E
Y
L
A
V
V
N
G
I
D
V
L
E
M
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
50.6
99.5
98.5
N.A.
96
97.8
N.A.
63.8
86.3
53
67.9
N.A.
N.A.
N.A.
N.A.
32.5
Protein Similarity:
100
50.6
99.5
98.5
N.A.
97.5
98.2
N.A.
78.4
90.2
67.2
75
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
100
6.6
100
100
N.A.
93.3
93.3
N.A.
73.3
100
40
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
100
100
66.6
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% A
% Cys:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
73
0
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
10
0
0
0
73
10
% G
% His:
46
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
28
0
19
0
73
0
0
10
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
10
0
0
10
0
10
0
73
0
64
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
19
0
0
0
10
0
10
10
64
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
10
0
0
10
73
% P
% Gln:
0
0
0
0
19
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
19
10
0
0
55
0
0
0
10
0
0
10
0
0
0
% R
% Ser:
0
0
0
19
0
0
0
64
0
0
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
73
0
0
10
0
0
0
73
0
0
% T
% Val:
10
55
10
0
10
10
55
0
0
0
10
19
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
64
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _