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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VANGL1 All Species: 29.7
Human Site: S446 Identified Species: 72.59
UniProt: Q8TAA9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TAA9 NP_620409.1 524 59975 S446 A F L E R Y L S A G P T L Q Y
Chimpanzee Pan troglodytes XP_513676 524 59944 S446 A F L E R Y L S A G P T L Q Y
Rhesus Macaque Macaca mulatta XP_001115459 590 67361 A512 A F L E R Y L A A G P T I Q Y
Dog Lupus familis XP_540251 524 59825 S446 A F L E R Y L S A G P T L Q Y
Cat Felis silvestris
Mouse Mus musculus Q80Z96 526 60031 S448 A F L E R Y L S A G P T L Q Y
Rat Rattus norvegicus NP_001103054 526 60086 S448 A F L E R Y L S A G P T L Q Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001232441 524 59613 S446 A F L E R Y L S P G P T L Q Y
Frog Xenopus laevis Q90X64 521 60078 G443 A F L E R Y L G P G P T I Q Y
Zebra Danio Brachydanio rerio Q8UVJ6 526 60063 T448 A F L E R Y L T P G P T M Q Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477177 581 65856 T503 A F L E P Y L T E S P V M Q S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 64.4 96.5 N.A. 94.8 95 N.A. N.A. 88.3 72.9 66.5 N.A. 43.2 N.A. N.A. N.A.
Protein Similarity: 100 99.8 76.6 98.6 N.A. 97.7 97.7 N.A. N.A. 94 85.3 80.6 N.A. 62.3 N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 100 N.A. 100 100 N.A. N.A. 93.3 80 80 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 86.6 93.3 N.A. 66.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 100 0 0 0 0 0 0 10 60 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 100 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 10 0 90 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 100 0 0 0 100 0 0 0 0 0 60 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 20 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 30 0 100 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 % Q
% Arg: 0 0 0 0 90 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 60 0 10 0 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 20 0 0 0 90 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 90 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _