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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
31.21
Human Site:
Y348
Identified Species:
62.42
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
Y348
D
T
Y
N
T
L
K
Y
A
N
R
A
K
D
I
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
Y348
D
T
Y
N
T
L
K
Y
A
N
R
A
K
D
I
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
Y348
D
T
Y
N
T
L
K
Y
A
N
R
A
K
D
I
Dog
Lupus familis
XP_542544
899
102337
Y348
D
T
Y
N
T
L
K
Y
A
N
R
A
K
D
I
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
Y348
D
T
Y
N
T
L
K
Y
A
N
R
A
K
E
I
Rat
Rattus norvegicus
Q4KLL9
826
91176
Y346
D
T
Y
N
T
L
K
Y
A
D
R
A
K
E
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
A229
D
T
S
S
R
S
H
A
V
F
Q
I
Y
L
N
Chicken
Gallus gallus
Q5ZLK6
797
86563
I317
T
R
L
L
K
D
S
I
G
G
N
C
R
T
I
Frog
Xenopus laevis
Q7ZXX2
997
114958
Y339
E
S
R
N
T
L
T
Y
A
D
R
A
K
N
I
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
Y346
D
T
H
N
T
L
K
Y
A
N
R
A
K
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
A237
V
A
G
L
K
I
I
A
I
Q
S
A
E
E
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
A219
E
S
S
S
R
S
H
A
I
F
T
I
T
L
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
13.3
6.6
60
86.6
N.A.
N.A.
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
26.6
13.3
86.6
100
N.A.
N.A.
33.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
25
67
0
0
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
67
0
0
0
0
9
0
0
0
17
0
0
0
34
0
% D
% Glu:
17
0
0
0
0
0
0
0
0
0
0
0
9
34
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
9
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
17
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
9
9
17
0
0
17
0
0
75
% I
% Lys:
0
0
0
0
17
0
59
0
0
0
0
0
67
0
0
% K
% Leu:
0
0
9
17
0
67
0
0
0
0
0
0
0
17
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
67
0
0
0
0
0
50
9
0
0
9
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Q
% Arg:
0
9
9
0
17
0
0
0
0
0
67
0
9
0
0
% R
% Ser:
0
17
17
17
0
17
9
0
0
0
9
0
0
0
0
% S
% Thr:
9
67
0
0
67
0
9
0
0
0
9
0
9
9
0
% T
% Val:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
0
0
0
67
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _