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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
19.39
Human Site:
T489
Identified Species:
38.79
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
T489
H
R
L
A
M
L
K
T
R
R
S
Y
L
E
K
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
T489
H
R
L
A
M
L
K
T
R
R
S
Y
L
E
K
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
T489
H
R
L
A
M
L
K
T
R
R
C
Y
L
E
K
Dog
Lupus familis
XP_542544
899
102337
T489
H
R
L
A
M
L
K
T
R
R
F
Y
L
E
K
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
T489
H
R
L
E
K
L
K
T
N
S
C
F
L
E
K
Rat
Rattus norvegicus
Q4KLL9
826
91176
D468
E
Q
E
Q
P
P
Q
D
K
Q
F
P
T
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
A351
T
L
K
Y
A
N
R
A
K
E
I
K
S
S
L
Chicken
Gallus gallus
Q5ZLK6
797
86563
Q439
Q
Q
E
L
G
A
G
Q
D
A
Q
L
G
G
E
Frog
Xenopus laevis
Q7ZXX2
997
114958
W472
K
T
R
R
A
R
K
W
R
D
E
H
R
K
E
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
S483
R
K
L
A
S
L
K
S
H
Q
E
H
L
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
C359
K
D
S
L
G
G
N
C
Q
T
V
M
I
A
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
N341
R
Y
A
N
R
A
K
N
I
K
N
K
A
K
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
93.3
93.3
N.A.
60
0
N.A.
0
0
13.3
33.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
93.3
93.3
N.A.
66.6
33.3
N.A.
13.3
13.3
33.3
73.3
N.A.
N.A.
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
42
17
17
0
9
0
9
0
0
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
17
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
9
9
9
0
0
0
0
0
% D
% Glu:
9
0
17
9
0
0
0
0
0
9
17
0
0
42
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
9
0
0
0
% F
% Gly:
0
0
0
0
17
9
9
0
0
0
0
0
9
9
0
% G
% His:
42
0
0
0
0
0
0
0
9
0
0
17
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
9
% I
% Lys:
17
9
9
0
9
0
67
0
17
9
0
17
0
17
42
% K
% Leu:
0
9
50
17
0
50
0
0
0
0
0
9
50
0
9
% L
% Met:
0
0
0
0
34
0
0
0
0
0
0
9
0
0
9
% M
% Asn:
0
0
0
9
0
9
9
9
9
0
9
0
0
0
9
% N
% Pro:
0
0
0
0
9
9
0
0
0
0
0
9
0
0
0
% P
% Gln:
9
17
0
9
0
0
9
9
9
17
9
0
0
17
9
% Q
% Arg:
17
42
9
9
9
9
9
0
42
34
0
0
9
0
0
% R
% Ser:
0
0
9
0
9
0
0
9
0
9
17
0
9
9
0
% S
% Thr:
9
9
0
0
0
0
0
42
0
9
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
9
0
0
0
0
0
0
0
34
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _