KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
13.03
Human Site:
S859
Identified Species:
26.06
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S859
K
R
V
R
Q
D
N
S
S
E
K
H
L
Q
E
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S859
K
R
V
R
Q
D
N
S
S
D
K
H
L
Q
E
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S858
K
R
V
R
Q
D
N
S
S
D
K
H
L
Q
E
Dog
Lupus familis
XP_542544
899
102337
A860
K
R
V
R
Q
D
D
A
S
E
K
V
L
Q
E
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
S847
K
R
I
R
R
D
N
S
S
V
K
P
M
Q
E
Rat
Rattus norvegicus
Q4KLL9
826
91176
R788
R
P
S
V
S
R
G
R
S
C
I
A
R
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
V671
I
D
G
K
E
L
N
V
E
V
D
G
P
S
L
Chicken
Gallus gallus
Q5ZLK6
797
86563
L759
V
S
N
A
S
R
S
L
G
G
I
Q
S
H
I
Frog
Xenopus laevis
Q7ZXX2
997
114958
V946
P
Q
N
Q
T
T
T
V
F
K
M
A
E
Q
Q
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
R847
S
K
P
L
R
I
R
R
L
G
V
S
S
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
K679
H
P
L
D
E
Q
N
K
D
G
Y
I
I
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
M661
Y
N
L
E
G
G
G
M
K
Y
K
P
S
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
93.3
93.3
80
N.A.
66.6
6.6
N.A.
6.6
0
6.6
0
N.A.
N.A.
6.6
N.A.
13.3
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
13.3
N.A.
20
6.6
33.3
20
N.A.
N.A.
40
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
9
0
0
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
9
0
9
0
42
9
0
9
17
9
0
0
0
9
% D
% Glu:
0
0
0
9
17
0
0
0
9
17
0
0
9
9
42
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
9
9
17
0
9
25
0
9
0
0
9
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
25
0
9
0
% H
% Ile:
9
0
9
0
0
9
0
0
0
0
17
9
9
0
9
% I
% Lys:
42
9
0
9
0
0
0
9
9
9
50
0
0
9
0
% K
% Leu:
0
0
17
9
0
9
0
9
9
0
0
0
34
9
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
9
0
9
0
0
% M
% Asn:
0
9
17
0
0
0
50
0
0
0
0
0
0
0
9
% N
% Pro:
9
17
9
0
0
0
0
0
0
0
0
17
9
0
9
% P
% Gln:
0
9
0
9
34
9
0
0
0
0
0
9
0
59
9
% Q
% Arg:
9
42
0
42
17
17
9
17
0
0
0
0
9
0
0
% R
% Ser:
9
9
9
0
17
0
9
34
50
0
0
9
25
9
0
% S
% Thr:
0
0
0
0
9
9
9
0
0
0
0
0
0
0
0
% T
% Val:
9
0
34
9
0
0
0
17
0
17
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
0
0
9
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _