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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
18.79
Human Site:
S841
Identified Species:
37.58
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S841
T
S
S
T
S
N
S
S
L
T
A
D
V
N
S
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S841
T
S
S
T
S
N
S
S
L
T
A
D
V
N
S
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S840
T
S
S
T
S
N
T
S
L
T
A
D
I
N
S
Dog
Lupus familis
XP_542544
899
102337
S842
T
S
S
A
S
N
T
S
L
T
A
E
V
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
S829
M
S
S
T
S
N
A
S
I
K
S
D
E
S
C
Rat
Rattus norvegicus
Q4KLL9
826
91176
T770
G
R
K
P
S
L
P
T
T
T
A
S
K
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
I653
I
E
D
H
E
G
Y
I
G
R
R
E
L
I
E
Chicken
Gallus gallus
Q5ZLK6
797
86563
S741
I
P
K
P
S
S
I
S
K
G
S
V
Q
K
R
Frog
Xenopus laevis
Q7ZXX2
997
114958
K928
N
T
L
Q
T
N
R
K
I
M
L
P
I
A
Q
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
P829
S
Q
A
M
A
A
A
P
K
R
I
K
R
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
P661
S
V
M
H
L
M
D
P
L
N
N
E
M
P
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
G643
K
D
K
S
L
A
Y
G
E
A
D
L
S
N
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
86.6
73.3
N.A.
46.6
20
N.A.
0
13.3
6.6
0
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
26.6
N.A.
13.3
26.6
33.3
33.3
N.A.
N.A.
26.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
9
9
17
17
0
0
9
42
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
9
9
0
0
0
9
0
0
0
9
34
0
9
0
% D
% Glu:
0
9
0
0
9
0
0
0
9
0
0
25
9
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
9
0
9
9
9
0
0
0
0
0
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
17
0
0
0
0
0
9
9
17
0
9
0
17
9
0
% I
% Lys:
9
0
25
0
0
0
0
9
17
9
0
9
9
17
0
% K
% Leu:
0
0
9
0
17
9
0
0
42
0
9
9
9
0
0
% L
% Met:
9
0
9
9
0
9
0
0
0
9
0
0
9
0
0
% M
% Asn:
9
0
0
0
0
50
0
0
0
9
9
0
0
42
0
% N
% Pro:
0
9
0
17
0
0
9
17
0
0
0
9
0
9
17
% P
% Gln:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
9
0
0
0
0
9
0
0
17
9
0
9
0
17
% R
% Ser:
17
42
42
9
59
9
17
50
0
0
17
9
9
9
25
% S
% Thr:
34
9
0
34
9
0
17
9
9
42
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
0
0
0
0
0
9
25
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _