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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
11.82
Human Site:
S741
Identified Species:
23.64
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S741
A
I
S
S
N
I
N
S
D
N
C
L
K
M
L
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S741
A
I
S
S
N
V
N
S
D
N
C
L
K
M
L
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S741
A
I
S
S
N
I
N
S
D
N
S
Q
K
M
C
Dog
Lupus familis
XP_542544
899
102337
G743
T
I
S
S
N
V
N
G
E
N
S
L
K
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
R741
N
S
Q
K
A
L
C
R
I
E
S
P
L
S
R
Rat
Rattus norvegicus
Q4KLL9
826
91176
R682
S
S
P
S
P
S
S
R
V
C
P
A
T
V
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
H565
A
S
L
Q
E
Q
Q
H
K
R
T
E
N
V
L
Chicken
Gallus gallus
Q5ZLK6
797
86563
C653
P
C
C
T
P
K
I
C
P
L
T
V
T
K
R
Frog
Xenopus laevis
Q7ZXX2
997
114958
T839
S
E
D
N
L
S
S
T
T
G
E
I
V
A
V
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
S739
S
S
I
F
D
P
N
S
T
I
D
I
G
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
H573
R
L
Q
Q
Q
Y
E
H
A
K
K
V
S
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
K555
W
T
M
L
M
Q
A
K
S
E
V
A
D
M
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
93.3
80
60
N.A.
0
6.6
N.A.
13.3
0
0
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
80
73.3
N.A.
6.6
33.3
N.A.
20
13.3
40
40
N.A.
N.A.
20
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
34
0
0
0
9
0
9
0
9
0
0
17
0
9
0
% A
% Cys:
0
9
9
0
0
0
9
9
0
9
17
0
0
0
9
% C
% Asp:
0
0
9
0
9
0
0
0
25
0
9
0
9
0
0
% D
% Glu:
0
9
0
0
9
0
9
0
9
17
9
9
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
9
0
0
9
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
9
0
% H
% Ile:
0
34
9
0
0
17
9
0
9
9
0
17
0
0
17
% I
% Lys:
0
0
0
9
0
9
0
9
9
9
9
0
34
9
0
% K
% Leu:
0
9
9
9
9
9
0
0
0
9
0
25
9
0
42
% L
% Met:
0
0
9
0
9
0
0
0
0
0
0
0
0
34
0
% M
% Asn:
9
0
0
9
34
0
42
0
0
34
0
0
9
9
0
% N
% Pro:
9
0
9
0
17
9
0
0
9
0
9
9
0
0
0
% P
% Gln:
0
0
17
17
9
17
9
0
0
0
0
9
0
0
9
% Q
% Arg:
9
0
0
0
0
0
0
17
0
9
0
0
0
0
17
% R
% Ser:
25
34
34
42
0
17
17
34
9
0
25
0
9
9
0
% S
% Thr:
9
9
0
9
0
0
0
9
17
0
17
0
17
9
0
% T
% Val:
0
0
0
0
0
17
0
0
9
0
9
17
9
17
9
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _