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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
9.09
Human Site:
S731
Identified Species:
18.18
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S731
K
P
S
S
F
T
T
S
F
Q
A
I
S
S
N
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S731
K
P
S
S
F
T
T
S
F
Q
A
I
S
S
N
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S731
K
P
S
S
F
T
T
S
F
Q
A
I
S
S
N
Dog
Lupus familis
XP_542544
899
102337
R733
K
P
L
S
Q
A
T
R
F
Q
T
I
S
S
N
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
M731
S
S
Q
S
A
N
V
M
N
D
N
S
Q
K
A
Rat
Rattus norvegicus
Q4KLL9
826
91176
E672
E
P
R
T
P
K
G
E
R
A
S
S
P
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
M555
K
T
Q
V
R
H
V
M
D
L
A
S
L
Q
E
Chicken
Gallus gallus
Q5ZLK6
797
86563
P643
L
K
E
P
Q
S
P
P
L
L
P
C
C
T
P
Frog
Xenopus laevis
Q7ZXX2
997
114958
H829
F
P
S
S
S
L
H
H
A
A
S
E
D
N
L
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
P729
Q
F
T
P
E
G
Q
P
H
T
S
S
I
F
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
K563
L
D
A
E
V
K
L
K
K
S
R
L
Q
Q
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
K545
H
G
K
T
K
K
L
K
K
V
W
T
M
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
100
100
66.6
N.A.
6.6
13.3
N.A.
13.3
0
20
0
N.A.
N.A.
0
N.A.
0
P-Site Similarity:
100
100
100
66.6
N.A.
6.6
33.3
N.A.
13.3
13.3
33.3
26.6
N.A.
N.A.
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
9
0
9
9
0
0
9
17
34
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
9
9
0
0
9
0
9
% D
% Glu:
9
0
9
9
9
0
0
9
0
0
0
9
0
0
9
% E
% Phe:
9
9
0
0
25
0
0
0
34
0
0
0
0
9
0
% F
% Gly:
0
9
0
0
0
9
9
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
9
9
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
34
9
0
0
% I
% Lys:
42
9
9
0
9
25
0
17
17
0
0
0
0
9
0
% K
% Leu:
17
0
9
0
0
9
17
0
9
17
0
9
9
9
9
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
9
% M
% Asn:
0
0
0
0
0
9
0
0
9
0
9
0
0
9
34
% N
% Pro:
0
50
0
17
9
0
9
17
0
0
9
0
9
0
17
% P
% Gln:
9
0
17
0
17
0
9
0
0
34
0
0
17
17
9
% Q
% Arg:
0
0
9
0
9
0
0
9
9
0
9
0
0
0
0
% R
% Ser:
9
9
34
50
9
9
0
25
0
9
25
34
34
42
0
% S
% Thr:
0
9
9
17
0
25
34
0
0
9
9
9
0
9
0
% T
% Val:
0
0
0
9
9
0
17
0
0
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _