KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF18A
All Species:
16.67
Human Site:
S687
Identified Species:
33.33
UniProt:
Q8NI77
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NI77
NP_112494.3
898
102281
S687
H
T
L
K
S
P
P
S
Q
S
V
Q
L
N
D
Chimpanzee
Pan troglodytes
XP_001138074
898
102191
S687
H
A
L
K
S
P
P
S
Q
S
V
Q
L
N
D
Rhesus Macaque
Macaca mulatta
XP_001089262
897
102178
S687
H
T
L
K
S
P
P
S
Q
S
V
Q
L
N
D
Dog
Lupus familis
XP_542544
899
102337
S689
H
P
Q
K
S
A
L
S
E
S
L
E
L
N
D
Cat
Felis silvestris
Mouse
Mus musculus
Q91WD7
886
100916
S687
H
T
Q
K
S
A
L
S
E
S
T
Q
L
N
D
Rat
Rattus norvegicus
Q4KLL9
826
91176
L628
E
K
K
R
K
L
N
L
E
E
P
G
S
L
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511000
709
81248
L511
F
G
E
N
T
N
W
L
R
Q
V
Q
D
E
I
Chicken
Gallus gallus
Q5ZLK6
797
86563
R599
S
E
M
S
N
T
S
R
L
E
T
P
H
S
L
Frog
Xenopus laevis
Q7ZXX2
997
114958
R785
I
A
V
K
A
A
R
R
R
S
R
V
L
E
G
Zebra Danio
Brachydanio rerio
NP_956533
895
100965
R685
G
V
L
K
K
P
I
R
R
K
L
S
V
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119963
717
81330
S519
E
Q
N
A
S
G
K
S
R
V
N
K
S
L
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P46872
699
78679
E501
L
L
E
Q
S
A
L
E
M
K
E
R
M
A
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
96.7
85.8
N.A.
75.8
35.5
N.A.
57.4
37.8
28.9
46.2
N.A.
N.A.
34.8
N.A.
27.8
Protein Similarity:
100
99.8
98.3
91.8
N.A.
84.9
52.2
N.A.
67.4
53.2
50.2
62.6
N.A.
N.A.
50
N.A.
45.6
P-Site Identity:
100
93.3
100
53.3
N.A.
66.6
0
N.A.
13.3
0
20
20
N.A.
N.A.
13.3
N.A.
6.6
P-Site Similarity:
100
93.3
100
73.3
N.A.
73.3
13.3
N.A.
26.6
20
40
46.6
N.A.
N.A.
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
9
9
34
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
42
% D
% Glu:
17
9
17
0
0
0
0
9
25
17
9
9
0
17
0
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
9
0
0
0
9
0
0
0
0
0
9
0
0
9
% G
% His:
42
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% H
% Ile:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% I
% Lys:
0
9
9
59
17
0
9
0
0
17
0
9
0
0
9
% K
% Leu:
9
9
34
0
0
9
25
17
9
0
17
0
50
17
9
% L
% Met:
0
0
9
0
0
0
0
0
9
0
0
0
9
0
0
% M
% Asn:
0
0
9
9
9
9
9
0
0
0
9
0
0
42
0
% N
% Pro:
0
9
0
0
0
34
25
0
0
0
9
9
0
0
17
% P
% Gln:
0
9
17
9
0
0
0
0
25
9
0
42
0
0
0
% Q
% Arg:
0
0
0
9
0
0
9
25
34
0
9
9
0
0
0
% R
% Ser:
9
0
0
9
59
0
9
50
0
50
0
9
17
17
0
% S
% Thr:
0
25
0
0
9
9
0
0
0
0
17
0
0
0
0
% T
% Val:
0
9
9
0
0
0
0
0
0
9
34
9
9
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _